# Histone deacetylase 5

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5773160](https://www.wikidata.org/wiki/Q5773160)  
**Source**: https://4ort.xyz/entity/histone-deacetylase-5


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UQL6)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
6. [Involvement of Epac1/Rap1/CaMKI/HDAC5 signaling cascade in the regulation of placental cell fusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
7. [Human BAHD1 promotes heterochromatic gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
8. [Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
9. [Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
10. [Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
11. [BCoR, a novel corepressor involved in BCL-6 repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
12. [Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
13. [Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
14. [Runx3 Inactivation Is a Crucial Early Event in the Development of Lung Adenocarcinoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
15. [The functional interactome landscape of the human histone deacetylase family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
16. [Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
17. [Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
18. [Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
19. [An expression screen reveals modulators of class II histone deacetylase phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
20. [Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
21. [Protein kinase C‐related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
22. [Three proteins define a class of human histone deacetylases related to yeast Hda1p](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
23. [SUMO modification regulates the transcriptional activity of XBP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
24. [Transcriptional activation of hypoxia-inducible factor-1alpha by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
25. [Class II histone deacetylases: versatile regulators](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
26. [Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
27. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQL6&geneProductId=UniProtKB:Q9UQL6)
28. [HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
29. [Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
30. [AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
31. [Class II histone deacetylases confer signal responsiveness to the ankyrin-repeat proteins ANKRA2 and RFXANK.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6)
32. Ensembl Release 99