# Histone deacetylase 4

> mammalian protein found in Mus musculus

**Wikidata**: [Q21984935](https://www.wikidata.org/wiki/Q21984935)  
**Source**: https://4ort.xyz/entity/histone-deacetylase-4-q21984935


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q6NZM9)
3. Q20641742
4. [The DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
6. [Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
7. [HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
8. [mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
9. [Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
10. [Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
11. [Histone deacetylase inhibitor MS-275 stimulates bone formation in part by enhancing Dhx36-mediated TNAP transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
12. [Epigenetic Silencing of Cd8 Genes by ThPOK-Mediated Deacetylation during CD4 T Cell Differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
13. [A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
14. [Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
15. [Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
16. [Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
17. [Androgen receptor corepressor-19 kDa (ARR19), a leucine-rich protein that represses the transcriptional activity of androgen receptor through recruitment of histone deacetylase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
18. [Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
19. [SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
20. [Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
21. [SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
22. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6NZM9&geneProductId=UniProtKB:Q6NZM9)
23. [A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
24. [The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
25. [Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
26. [MEF2C transcription factor controls chondrocyte hypertrophy and bone development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
27. [Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
28. [Elevated microRNA-155 promotes foam cell formation by targeting HBP1 in atherogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6NZM9)
29. ensembl Release 106