# Histone deacetylase 3

> mammalian protein found in Mus musculus

**Wikidata**: [Q21984932](https://www.wikidata.org/wiki/Q21984932)  
**Source**: https://4ort.xyz/entity/histone-deacetylase-3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O88895)
3. Q20641742
4. [Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
5. [A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
7. [Class II histone deacetylases: versatile regulators](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88895&geneProductId=UniProtKB:O88895)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88895&geneProductId=UniProtKB:O88895)
9. [Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
10. [Leucine-rich repeat kinase 2 exacerbates neuronal cytotoxicity through phosphorylation of histone deacetylase 3 and histone deacetylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
11. [Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
12. [Class II histone deacetylases: versatile regulators](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
13. [The histone-binding code of nuclear receptor co-repressors matches the substrate specificity of histone deacetylase 3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
14. [Distinct Roles of HDAC3 in the Core Circadian Negative Feedback Loop Are Critical for Clock Function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
15. [Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
16. [The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
17. [Adipose is a conserved dosage-sensitive antiobesity gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
18. [Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
19. [NFATc1 mediates HDAC-dependent transcriptional repression of osteocalcin expression during osteoblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
20. [Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
21. [Chromatin regulation by Brg1 underlies heart muscle development and disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
22. [Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
23. [Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
24. [Regulation of nuclear translocation of HDAC3 by IkappaBalpha is required for tumor necrosis factor inhibition of peroxisome proliferator-activated receptor gamma function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
25. [Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
26. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
27. [Silencing ofFem1cR3Gene Expression in the DBA/2J Mouse Precedes Retinal Ganglion Cell Death and Is Associated with Histone Deacetylase Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
28. [Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88895&geneProductId=UniProtKB:O88895)
29. [Cloning and expression of a murine histone deacetylase 3 (mHdac3) cDNA and mapping to a region of conserved synteny between murine chromosome 18 and human chromosome 5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
30. [JDP2 suppresses adipocyte differentiation by regulating histone acetylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
31. [Leucine-rich repeat kinase 2 exacerbates neuronal cytotoxicity through phosphorylation of histone deacetylase 3 and histone deacetylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88895&geneProductId=UniProtKB:O88895)
32. [Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88895)
33. ensembl Release 106