# Histone deacetylase 3

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28563299](https://www.wikidata.org/wiki/Q28563299)  
**Source**: https://4ort.xyz/entity/histone-deacetylase-3-q28563299


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q6P6W3)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
5. [Histone Deacetylase 3 Mediates Allergic Skin Inflammation by Regulating Expression of MCP1 Protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
6. [Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
8. [HDAC3 interacts with sumoylated C/EBPα to negatively regulate the LXRα expression in rat hepatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
9. [HDAC inhibition suppresses cardiac hypertrophy and fibrosis in DOCA-salt hypertensive rats via regulation of HDAC6/HDAC8 enzyme activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
10. [Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
11. [High expression of liver histone deacetylase 3 contributes to high-fat-diet-induced metabolic syndrome by suppressing the PPAR-γ and LXR-α-pathways in E3 rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
12. [Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
13. [Selective Toxicity by HDAC3 in Neurons: Regulation by Akt and GSK3β](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
14. [In Cortical Neurons HDAC3 Activity Suppresses RD4-Dependent SMRT Export](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
15. [Histone deacetylases modulate vascular smooth muscle cell migration induced by cyclic mechanical strain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
16. [HDAC4 represses matrix metalloproteinase-13 transcription in osteoblastic cells, and parathyroid hormone controls this repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
17. [Sepsis and glucocorticoids upregulate p300 and downregulate HDAC6 expression and activity in skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
18. [Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6W3)
19. ensembl Release 106