# Histone deacetylase 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21984934](https://www.wikidata.org/wiki/Q21984934)  
**Source**: https://4ort.xyz/entity/histone-deacetylase-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P70288)
3. Q20641742
4. [Opposing LSD1 complexes function in developmental gene activation and repression programmes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
5. [Histone Deacetylase 2 (HDAC2) Regulates Chromosome Segregation and Kinetochore Function via H4K16 Deacetylation during Oocyte Maturation in Mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
6. [A Novel KRAB Domain-containing Zinc Finger Transcription Factor ZNF431 Directly Represses Patched1 Transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
7. [ZFP932 Suppresses Cellular Hedgehog Response and Patched1 Transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
8. [Class II histone deacetylases: versatile regulators](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
10. [GAPDH mediates nitrosylation of nuclear proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
11. [S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
12. [CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
13. [LHX2 Interacts with the NuRD Complex and Regulates Cortical Neuron Subtype Determinants Fezf2 and Sox11.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
14. [Repression of Six3 by a corepressor regulates rhodopsin expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
15. [Circadian and light-induced transcription of clock gene Per1 depends on histone acetylation and deacetylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
16. [HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
17. [Murine Sall1 represses transcription by recruiting a histone deacetylase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
18. [Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
19. [Hopx and Hdac2 Interact to Modulate Gata4 Acetylation and Embryonic Cardiac Myocyte Proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
20. [DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
21. [Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
22. [The Mad1-Sin3B interaction involves a novel helical fold](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
23. [Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
24. [Chromatin regulation by Brg1 underlies heart muscle development and disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
25. [Enhancer decommissioning by LSD1 during embryonic stem cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
26. [HDAC2 negatively regulates memory formation and synaptic plasticity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
27. [Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
28. [Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
29. [Class II histone deacetylases: versatile regulators](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70288&geneProductId=UniProtKB:P70288)
30. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70288&geneProductId=UniProtKB:P70288)
31. [S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70288&geneProductId=UniProtKB:P70288)
32. [Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
33. [The primary microRNA-208b interacts with Polycomb-group protein, Ezh2, to regulate gene expression in the heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
34. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
35. [Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
36. [An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
37. [Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted expression of H19 and Peg3 during mouse preimplantation development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
38. [The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
39. [Expression and localization of components of the histone deacetylases multiprotein repressory complexes in the mouse preimplantation embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
40. [Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
41. [Hdac1 and Hdac2 Act Redundantly to Control p63 and p53 Functions in Epidermal Progenitor Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
42. [Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
43. [Circadian and light-induced transcription of clock gene Per1 depends on histone acetylation and deacetylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70288&geneProductId=UniProtKB:P70288)
44. [RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
45. [Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
46. [Elevated microRNA-155 promotes foam cell formation by targeting HBP1 in atherogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70288)
47. ensembl Release 106