# Histone deacetylase 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561057](https://www.wikidata.org/wiki/Q28561057)  
**Source**: https://4ort.xyz/entity/histone-deacetylase-1-q28561057


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q4QQW4)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
5. [Dexamethasone Induces a Putative Repressor Complex and Chromatin Modifications in the CRH Promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
6. [Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
8. [DeltaNp73 modulates nerve growth factor-mediated neuronal differentiation through repression of TrkA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
9. [Members of the NuRD chromatin remodeling complex interact with AUF1 in developing cortical neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
10. [HDAC inhibition suppresses cardiac hypertrophy and fibrosis in DOCA-salt hypertensive rats via regulation of HDAC6/HDAC8 enzyme activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
11. [Induction of a novel histone deacetylase 1/c-Myc/Mnt/Max complex formation is implicated in parity-induced refractoriness to mammary carcinogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
12. [HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
13. [Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
14. [HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
15. [Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
16. [Histone deacetylase 1/2 mediates proliferation of renal interstitial fibroblasts and expression of cell cycle proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
17. [Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
18. [Lipopolysaccharide Induces Up-Regulation of TGF-α through HDAC2 in a Rat Model of Bronchopulmonary Dysplasia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
19. [Lipopolysaccharide induces epididymal and testicular antimicrobial gene expression in vitro: insights into the epigenetic regulation of sperm-associated antigen 11e gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
20. [Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
21. [Oxidative stress regulates IGF1R expression in vascular smooth-muscle cells via p53 and HDAC recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
22. [Regulation of neuron survival and death by p130 and associated chromatin modifiers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
23. [Differential Modulation of the Oligodendrocyte Transcriptome by Sonic Hedgehog and Bone Morphogenetic Protein 4 via Opposing Effects on Histone Acetylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
24. [Hyperoxia arrests alveolar development through suppression of histone deacetylases in neonatal rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4QQW4)
25. ensembl Release 106