# Histone deacetylase 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q14914426](https://www.wikidata.org/wiki/Q14914426)  
**Source**: https://4ort.xyz/entity/histone-deacetylase-1-q14914426


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O09106)
3. Q20641742
4. [HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment](http://www.ebi.ac.uk/QuickGO/annotations?protein=O09106&geneProductId=UniProtKB:O09106)
5. [Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3](http://www.ebi.ac.uk/QuickGO/annotations?protein=O09106&geneProductId=UniProtKB:O09106)
6. [Functional architecture of atrophins](http://www.ebi.ac.uk/QuickGO/annotations?protein=O09106&geneProductId=UniProtKB:O09106)
7. [Opposing LSD1 complexes function in developmental gene activation and repression programmes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O09106&geneProductId=UniProtKB:O09106)
9. [A Novel KRAB Domain-containing Zinc Finger Transcription Factor ZNF431 Directly Represses Patched1 Transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
11. [Circadian and light-induced transcription of clock gene Per1 depends on histone acetylation and deacetylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
12. [Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
13. [DNA methyltransferase Dnmt1 associates with histone deacetylase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
14. [Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
15. [A novel protein, CHRONO, functions as a core component of the mammalian circadian clock](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
16. [Stress-Induced C/EBP Homology Protein (CHOP) Represses MyoD Transcription to Delay Myoblast Differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
17. [The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
18. [Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
19. [Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
20. [Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
21. [The Developmental Regulator Protein Gon4l Associates with Protein YY1, Co-repressor Sin3a, and Histone Deacetylase 1 and Mediates Transcriptional Repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
22. [The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
23. [Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
24. [CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
25. [REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
26. [Mnt transcriptional repressor is functionally regulated during cell cycle progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
27. [Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
28. [HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
29. [Murine Sall1 represses transcription by recruiting a histone deacetylase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
30. [Metastasis-associated protein 3 (MTA3) regulates G2/M progression in proliferating mouse granulosa cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
31. [Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
32. [The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
33. [Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
34. [Znhit1 causes cell cycle arrest and down-regulates CDK6 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
35. [Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
36. [The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
37. [Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
38. [Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
39. [Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
40. [Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
41. [The NuRD component Mbd3 is required for pluripotency of embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
42. [Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
43. [Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
44. [HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
45. [Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
46. [Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
47. [Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
48. [LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
49. [C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)
50. [The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09106)