# Hippo Dmel_CG11228

> protein found in Drosophila melanogaster

**Wikidata**: [Q29813249](https://www.wikidata.org/wiki/Q29813249)  
**Source**: https://4ort.xyz/entity/hippo-dmel-cg11228


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8T0S6)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
6. [hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
7. [Dmp53 activates the Hippo pathway to promote cell death in response to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
8. [Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
9. [Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
10. [Dimerization and Cytoplasmic Localization Regulate Hippo Kinase Signaling Activity in Organ Size Control](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
11. [Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
12. [Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
13. [The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
14. [A protein interaction map of Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
15. [Par-1 Regulates Tissue Growth by Influencing Hippo Phosphorylation Status and Hippo-Salvador Association](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
16. [Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
17. [Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
18. [Dimerization and Cytoplasmic Localization Regulate Hippo Kinase Signaling Activity in Organ Size Control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
19. [hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
20. [Dmp53 activates the Hippo pathway to promote cell death in response to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
21. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
22. [Kibra and Merlin Activate the Hippo Pathway Spatially Distinct from and Independent of Expanded](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
23. [The bantam microRNA is a target of the hippo tumor-suppressor pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
24. [The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
25. [Protein kinases and phosphatases in the Drosophila genome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
26. [The Hippo pathway polarizes the actin cytoskeleton during collective migration of Drosophila border cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
27. [Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
28. [Hippo signalling controls Dronc activity to regulate organ size in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
29. [Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
30. [vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
31. [The growth regulators warts/lats and melted interact in a bistable loop to specify opposite fates in Drosophila R8 photoreceptors.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
32. [Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
33. [How are the sizes of cells, organs, and bodies controlled?](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
34. [Regulation ofDrosophilaglial cell proliferation by Merlin-Hippo signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
35. [Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
36. [Hippo signaling regulatesDrosophilaintestine stem cell proliferation through multiple pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
37. [The Hippo pathway regulates Wnt/beta-catenin signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
38. [Hippo Stabilises Its Adaptor Salvador by Antagonising the HECT Ubiquitin Ligase Herc4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
39. [Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
40. [The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
41. [The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
42. [The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8T0S6&geneProductId=UniProtKB:Q8T0S6)
43. [The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
44. [The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
45. [The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
46. [Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T0S6)
47. ensembl Release 106