# High mobility group box 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21984114](https://www.wikidata.org/wiki/Q21984114)  
**Source**: https://4ort.xyz/entity/high-mobility-group-box-1-q21984114


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P63158)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
5. [Identity in molecular structure between "differentiation enhancing factor" of murine erythroleukemia cells and the 30 kD heparin-binding protein of developing rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
6. [HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
7. [Extracellular release of the 'differentiation enhancing factor', a HMG1 protein type, is an early step in murine erythroleukemia cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
8. [CD24 and Siglec-10 selectively repress tissue damage-induced immune responses.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
9. [Phage display screening reveals an association between germline-specific transcription factor Oct-4 and multiple cellular proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
10. [Endogenous HMGB1 regulates autophagy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
11. [Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
13. [HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
15. [HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
17. [High mobility group 1 (HMG1) protein in mouse preimplantation embryos](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
18. [HMGB1, an architectural chromatin protein and extracellular signalling factor, has a spatially and temporally restricted expression pattern in mouse brain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
19. [HMGB1, an architectural chromatin protein and extracellular signalling factor, has a spatially and temporally restricted expression pattern in mouse brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
20. [High mobility group 1 (HMG1) protein in mouse preimplantation embryos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
21. [Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
22. [Exploring New Inflammatory Biomarkers and Pathways during LPS-Induced M1 Polarization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
23. [Extracellular release of the 'differentiation enhancing factor', a HMG1 protein type, is an early step in murine erythroleukemia cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
24. [Hepatoma-derived growth factor is a neurotrophic factor harbored in the nucleus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
25. [Hepatoma-derived growth factor is a neurotrophic factor harbored in the nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
26. [The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
27. [Cutting edge: extracellular high mobility group box-1 protein is a proangiogenic cytokine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
28. [HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
29. [CD24 and Siglec-10 selectively repress tissue damage-induced immune responses.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
30. [Tissue damage-associated "danger signals" influence T-cell responses that promote the progression of preneoplasia to cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
31. [High mobility group box 1 protein interacts with multiple Toll-like receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
32. [High mobility group box 1 protein interacts with multiple Toll-like receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
33. [High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
34. [HMGB1 is a cofactor in mammalian base excision repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
35. [Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
36. [Endogenous HMGB1 regulates autophagy](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
37. [The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
38. [Cutting edge: extracellular high mobility group box-1 protein is a proangiogenic cytokine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63158&geneProductId=UniProtKB:P63158)
39. [Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
40. [IL-7-induced phosphorylation of the adaptor Crk-like and other targets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63158)
41. ensembl Release 106