# Hierarchical Time-Lagged Independent Component Analysis: Computing Slow Modes and Reaction Coordinates for Large Molecular Systems

> Research article (Journal of Chemical Theory and Computation, 2016) · cited 79× · AI/ML

**Wikidata**: [openalex:W2540372843](https://www.wikidata.org/wiki/openalex:W2540372843)  
**Source**: https://4ort.xyz/entity/hierarchical-time-lagged-independent-component-analysis-computing-slow-modes-and-reaction-coordinates-for-large-molecula