# Hexokinase 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21118406](https://www.wikidata.org/wiki/Q21118406)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Hexokinase_II)  
**Source**: https://4ort.xyz/entity/hexokinase-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P52789)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
6. [Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
7. [Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
8. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
9. [c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
10. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P52789&geneProductId=UniProtKB:P52789)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P52789&geneProductId=UniProtKB:P52789)
13. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P52789&geneProductId=UniProtKB:P52789)
14. [Glucose catabolism in cancer cells. Isolation, sequence, and activity of the promoter for type II hexokinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
15. [Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
16. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
17. [Hexokinase activity is required for recruitment of parkin to depolarized mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
18. [Hexokinase activity is required for recruitment of parkin to depolarized mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?protein=P52789&geneProductId=UniProtKB:P52789)
19. [TGFβ Triggers miR-143/145 Transfer From Smooth Muscle Cells to Endothelial Cells, Thereby Modulating Vessel Stabilization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52789)
20. Ensembl Release 99