# HEXIM P-TEFb complex subunit 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21114044](https://www.wikidata.org/wiki/Q21114044)  
**Source**: https://4ort.xyz/entity/hexim-p-tefb-complex-subunit-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O94992)
3. Q20641742
4. [MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
5. [Specificity of Hexim1 and Hexim2 complex formation with cyclin T1/T2, importin alpha and 7SK snRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
6. [LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
7. [Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
8. [Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
9. [Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
10. [The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
11. [RNA helicase DDX21 coordinates transcription and ribosomal RNA processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
12. [Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
13. [RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
14. [Protein Phosphatase-1 Activates CDK9 by Dephosphorylating Ser175](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
15. [Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
16. [Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
17. [HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
18. [Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
19. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
20. [MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94992&geneProductId=UniProtKB:O94992)
21. [Specificity of Hexim1 and Hexim2 complex formation with cyclin T1/T2, importin alpha and 7SK snRNA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94992&geneProductId=UniProtKB:O94992)
22. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94992&geneProductId=UniProtKB:O94992)
23. [Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94992&geneProductId=UniProtKB:O94992)
24. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
25. [Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94992&geneProductId=UniProtKB:O94992)
26. [HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94992&geneProductId=UniProtKB:O94992)
27. [HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
28. [Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
29. [Identification of HEXIM1 as a Positive Regulator of p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94992)
30. Ensembl Release 99
31. UMLS 2023