# hereditary spastic paraplegia 3A

> hereditary spastic paraplegia that is characterized by lower limb weakness and spasticity that is generally non-progressive or extremely slow and has material basis in mutation in the ATL1 gene on chromosome 14q22

**Wikidata**: [Q32142983](https://www.wikidata.org/wiki/Q32142983)  
**Source**: https://4ort.xyz/entity/hereditary-spastic-paraplegia-3a


## References

1. Disease Ontology
2. Monarch Disease Ontology release 2018-06-29
3. UniProt
4. Mutations in a newly identified GTPase gene cause autosomal dominant hereditary spastic paraplegia
5. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000198513/MONDO_0008437)
6. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000198513/Orphanet_100984)
7. [Identifiers.org](https://registry.identifiers.org/registry/doid)