# hereditary leiomyomatosis and renal cell cancer syndrome

> Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a hereditary cancer syndrome characterized by a predisposition to cutaneous and uterine leiomyomas and, in some families, to renal cell cancer

**Wikidata**: [Q3270312](https://www.wikidata.org/wiki/Q3270312)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Hereditary_leiomyomatosis_and_renal_cell_cancer_syndrome)  
**Source**: https://4ort.xyz/entity/hereditary-leiomyomatosis-and-renal-cell-cancer-syndrome


## References

1. Monarch Disease Ontology release 2018-06-29
2. UniProt
3. Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
4. [ClinGen](https://search.clinicalgenome.org/kb/gene-validity/59e42ccd-2b0b-441c-8529-6eb1e9dde330--2020-02-19T22:29:53)
5. [ClinGen](https://search.clinicalgenome.org/kb/gene-validity/59e42ccd-2b0b-441c-8529-6eb1e9dde330--2020-05-14T00:23:34)
6. [ClinGen](https://search.clinicalgenome.org/kb/gene-validity/CGGV:assertion_59e42ccd-2b0b-441c-8529-6eb1e9dde330-2020-05-14T002334.007Z)
7. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000091483/MONDO_0007888)
8. Human Phenotype Ontology release 2018-03-08