# Hepsin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21106301](https://www.wikidata.org/wiki/Q21106301)  
**Source**: https://4ort.xyz/entity/hepsin


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P05981)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981)
5. [Pro-urokinase-type plasminogen activator is a substrate for hepsin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981)
6. [Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981)
7. [Human hepatitis B virus X protein promotes cell proliferation and inhibits cell apoptosis through interacting with a serine protease Hepsin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981)
8. [Hepsin activates prostasin and cleaves the extracellular domain of the epidermal growth factor receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981)
9. [Hepsin, a cell membrane-associated protease. Characterization, tissue distribution, and gene localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05981&geneProductId=UniProtKB:P05981)
11. [Pro-urokinase-type plasminogen activator is a substrate for hepsin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05981&geneProductId=UniProtKB:P05981)
12. [An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981)
13. [Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981)
14. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05981&geneProductId=UniProtKB:P05981)
15. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05981&geneProductId=UniProtKB:P05981)
16. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981)
17. [TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981)
18. [Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05981&geneProductId=UniProtKB:P05981)
19. [Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05981&geneProductId=UniProtKB:P05981)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05981)
21. Ensembl Release 99
22. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)