Heparan sulfate 6-O-sulfotransferase 1
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: O60243
additional property: PropertyValue
  property ID: P361
  value: Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase
additional property: PropertyValue
  property ID: P361
  value: P-loop containing nucleoside triphosphate hydrolase
additional property: PropertyValue
  property ID: P637
  value: NP_004798
additional property: PropertyValue
  property ID: P680
  value: transferase activity
additional property: PropertyValue
  property ID: P680
  value: sulfotransferase activity
additional property: PropertyValue
  property ID: P680
  value: heparan sulfate 6-O-sulfotransferase activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: Golgi membrane
additional property: PropertyValue
  property ID: P681
  value: integral component of plasma membrane
additional property: PropertyValue
  property ID: P682
  value: lung alveolus development
additional property: PropertyValue
  property ID: P682
  value: neuron development
additional property: PropertyValue
  property ID: P682
  value: labyrinthine layer blood vessel development
additional property: PropertyValue
  property ID: P702
  value: HS6ST1
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000259241
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 10
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 10
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: O60243
    source count: 1
    confidence: 0.2
  P361:
    value: Q24774369
    source count: 1
    confidence: 0.2
    value label: Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase
  P361:
    value: Q24726930
    source count: 1
    confidence: 0.2
    value label: P-loop containing nucleoside triphosphate hydrolase
  P637:
    value: NP_004798
    source count: 1
    confidence: 0.2
  P680:
    value: Q14840131
    source count: 1
    confidence: 0.2
    value label: transferase activity
  P680:
    value: Q21102365
    source count: 2
    confidence: 0.4
    value label: sulfotransferase activity
  P680:
    value: Q21107555
    source count: 3
    confidence: 0.6
    value label: heparan sulfate 6-O-sulfotransferase activity
  P680:
    value: Q21107555
    source count: 2
    confidence: 0.4
    value label: heparan sulfate 6-O-sulfotransferase activity
  P681:
    value: Q14327652
    source count: 2
    confidence: 0.4
    value label: integral component of membrane
  P681:
    value: Q14598778
    source count: 1
    confidence: 0.2
    value label: Golgi membrane
  P681:
    value: Q14859540
    source count: 1
    confidence: 0.2
    value label: integral component of plasma membrane
  P681:
    value: Q14349455
    source count: 1
    confidence: 0.2
    value label: membrane
  P682:
    value: Q14820063
    source count: 1
    confidence: 0.2
    value label: lung alveolus development
  P682:
    value: Q14865336
    source count: 1
    confidence: 0.2
    value label: neuron development
  P682:
    value: Q15317715
    source count: 1
    confidence: 0.2
    value label: labyrinthine layer blood vessel development
  P682:
    value: Q14914229
    source count: 1
    confidence: 0.2
    value label: heparan sulfate proteoglycan biosynthetic process
  P682:
    value: Q539568
    source count: 1
    confidence: 0.2
    value label: angiogenesis
  P702:
    value: Q18034059
    source count: 1
    confidence: 0.2
    value label: HS6ST1
  P703:
    value: Q15978631
    source count: 1
    confidence: 0.2
    value label: Homo sapiens
  P705:
    value: ENSP00000259241
    source count: 1
    confidence: 0.2
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2019-04-08
citations:
  source: Molecular characterization and expression of heparan-sulfate 6-sulfotransferase. Complete cDNA cloning in human and partial cloning in Chinese hamster ovary cells
  stated in qid: Q24322572
  retrieved: 2019-04-08
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2018-09-10
citations:
  source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
  stated in qid: Q34211397
  retrieved: 2018-09-10
citations:
  source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
  stated in qid: Q34211397
  retrieved: 2019-04-08
citations:
  source: Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism
  stated in qid: Q24307650
  retrieved: 2019-04-08
citations:
  source: InterPro Release 71.0
  stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21107556
domain: protein
level: standard
html url: https://4ort.xyz/entity/heparan-sulfate-6-o-sulfotransferase-1-q21107556
markdown url: https://4ort.xyz/entity/heparan-sulfate-6-o-sulfotransferase-1-q21107556.md
facts url summary: https://4ort.xyz/entity/heparan-sulfate-6-o-sulfotransferase-1-q21107556/facts.json
facts url standard: https://4ort.xyz/entity/heparan-sulfate-6-o-sulfotransferase-1-q21107556/facts.json
facts url full: https://4ort.xyz/entity/heparan-sulfate-6-o-sulfotransferase-1-q21107556/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-06T19:52:03.550604Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:57:03.164433+00:00Z