Hemopoietic cell kinase
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P08103
additional property: PropertyValue
  property ID: P361
  value: SH3-like domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Protein kinase-like domain superfamily
additional property: PropertyValue
  property ID: P361
  value: SH2 domain superfamily
additional property: PropertyValue
  property ID: P527
  value: SH2 domain
additional property: PropertyValue
  property ID: P527
  value: tyrosine-protein kinase, catalytic domain
additional property: PropertyValue
  property ID: P527
  value: tyrosine-protein kinase, active site
additional property: PropertyValue
  property ID: P637
  value: NP_001165588
additional property: PropertyValue
  property ID: P637
  value: NP_034537
additional property: PropertyValue
  property ID: P680
  value: transferase activity
additional property: PropertyValue
  property ID: P680
  value: nucleotide binding
additional property: PropertyValue
  property ID: P680
  value: protein kinase activity
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: cytosol
additional property: PropertyValue
  property ID: P681
  value: Golgi apparatus
additional property: PropertyValue
  property ID: P682
  value: cell differentiation
additional property: PropertyValue
  property ID: P682
  value: phosphorylation
additional property: PropertyValue
  property ID: P682
  value: transmembrane receptor protein tyrosine kinase signaling pathway
additional property: PropertyValue
  property ID: P702
  value: Hck
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000105423
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000141030
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000003370
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 9
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 9
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P08103
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797170
    source count: 1
    confidence: 0.2
    value label: SH3-like domain superfamily
  P361:
    value: Q24726164
    source count: 1
    confidence: 0.2
    value label: Protein kinase-like domain superfamily
  P361:
    value: Q41797956
    source count: 1
    confidence: 0.2
    value label: SH2 domain superfamily
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q83137014
    source count: 1
    confidence: 0.2
    value label: Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
  P527:
    value: Q24780316
    source count: 1
    confidence: 0.2
    value label: SH2 domain
  P527:
    value: Q24719835
    source count: 1
    confidence: 0.2
    value label: tyrosine-protein kinase, catalytic domain
  P527:
    value: Q24738472
    source count: 1
    confidence: 0.2
    value label: tyrosine-protein kinase, active site
  P527:
    value: Q24740842
    source count: 1
    confidence: 0.2
    value label: serine-threonine/tyrosine-protein kinase, catalytic domain
  P527:
    value: Q24771787
    source count: 1
    confidence: 0.2
    value label: SH3 domain
  P637:
    value: NP_001165588
    source count: 1
    confidence: 0.2
  P637:
    value: NP_034537
    source count: 1
    confidence: 0.2
  P680:
    value: Q14840131
    source count: 1
    confidence: 0.2
    value label: transferase activity
  P680:
    value: Q14860365
    source count: 1
    confidence: 0.2
    value label: nucleotide binding
  P680:
    value: Q14820641
    source count: 1
    confidence: 0.2
    value label: protein kinase activity
  P680:
    value: Q14873985
    source count: 2
    confidence: 0.4
    value label: non-membrane spanning protein tyrosine kinase activity
  P680:
    value: Q14863082
    source count: 1
    confidence: 0.2
    value label: kinase activity
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q220599
    source count: 1
    confidence: 0.2
    value label: cytosol
  P681:
    value: Q83181
    source count: 1
    confidence: 0.2
    value label: Golgi apparatus
  P681:
    value: Q14353100
    source count: 1
    confidence: 0.2
    value label: cell projection

value: Q14349455
source count: 1
confidence: 0.2
value label: membrane

value: Q210861
source count: 1
confidence: 0.2
value label: cell differentiation

value: Q242736
source count: 1
confidence: 0.2
value label: phosphorylation

value: Q14863362
source count: 1
confidence: 0.2
value label: transmembrane receptor protein tyrosine kinase signaling pathway

value: Q14916317
source count: 1
confidence: 0.2
value label: immune system process

value: Q7251493
source count: 1
confidence: 0.2
value label: protein phosphorylation

value: Q18251150
source count: 1
confidence: 0.2
value label: Hck

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000105423
source count: 1
confidence: 0.2

value: ENSMUSP00000141030
source count: 1
confidence: 0.2

value: ENSMUSP00000003370
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein
stated in qid: Q24306798
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-03-27

source: Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity
stated in qid: Q28504571
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21985344
domain: protein
level: standard
html url: https://4ort.xyz/entity/hemopoietic-cell-kinase
markdown url: https://4ort.xyz/entity/hemopoietic-cell-kinase.md
facts url summary: https://4ort.xyz/entity/hemopoietic-cell-kinase/facts.json
facts url standard: https://4ort.xyz/entity/hemopoietic-cell-kinase/facts.json
facts url full: https://4ort.xyz/entity/hemopoietic-cell-kinase/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-08T11:41:51.749130Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:25:40.090227+00:00Z