# Hemoglobin subunit alpha 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q1417916](https://www.wikidata.org/wiki/Q1417916)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Hemoglobin,_alpha_2)  
**Source**: https://4ort.xyz/entity/hemoglobin-subunit-alpha-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P69905)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P69905&geneProductId=UniProtKB:P69905)
6. [Peroxidase activity of hemoglobin-haptoglobin complexes: covalent aggregation and oxidative stress in plasma and macrophages](http://www.ebi.ac.uk/QuickGO/annotations?protein=P69905&geneProductId=UniProtKB:P69905)
7. [Translational regulation of human papillomavirus type 16 E7 mRNA by the peptide SEQIKA, shared by rabbit alpha(1)-globin and human cytokeratin 7.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
8. [A human protein-protein interaction network: a resource for annotating the proteome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
9. [LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
10. [Crystal structure of deoxy-human hemoglobin beta6 Glu --> Trp. Implications for the structure and formation of the sickle cell fiber](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
11. [The Use of Electron Tomography for Structural Analysis of Disordered Protein Arrays](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
12. [HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
13. [Endothelial cell expression of haemoglobin α regulates nitric oxide signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
14. [Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
15. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
16. [A human recombinant haemoglobin designed for use as a blood substitute](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
17. [Modulation of ligand binding in engineered human hemoglobin distal pocket](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
18. [Expression, purification, and characterization of human hemoglobins Gower-1 (zeta(2)epsilon(2)), Gower-2 (alpha(2)epsilon(2)), and Portland-2 (zeta(2)beta(2)) assembled in complex transgenic-knockout mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
19. [Genetically crosslinked hemoglobin: a structural study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
20. [Structural and functional properties of human hemoglobins reassembled after synthesis in Escherichia coli](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
21. [Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
22. [Control of heme reactivity by diffusion: structural basis and functional characterization in hemoglobin mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
23. [Separation of zeta (zeta) and various gamma (gamma) chains of human embryonic hemoglobin Portland I by reverse-phase high-performance liquid chromatography](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
24. [Peroxidase activity of hemoglobin-haptoglobin complexes: covalent aggregation and oxidative stress in plasma and macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
25. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
26. [Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability](http://www.ebi.ac.uk/QuickGO/annotations?protein=P69905&geneProductId=UniProtKB:P69905)
27. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P69905&geneProductId=UniProtKB:P69905)
28. [Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
29. [The multiple functions of hemoglobin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P69905&geneProductId=UniProtKB:P69905)
30. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P69905&geneProductId=UniProtKB:P69905)
31. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P69905&geneProductId=UniProtKB:P69905)
32. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P69905&geneProductId=UniProtKB:P69905)
33. [Innate immunity proteins and a new truncated form of SPLUNC1 in nasopharyngeal aspirates from infants with respiratory syncytial virus infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
34. [The multiple functions of hemoglobin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
35. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
36. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
37. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
38. [Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
39. [Functional alterations in adult and fetal hemoglobin Sassari Asp-alpha 126(H9)-->His. The role of alpha 1 alpha 2 contact](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P69905)
40. Ensembl Release 99
41. Transporter Classification database