# Hemipterous Dmel_CG4353

> protein found in Drosophila melanogaster

**Wikidata**: [Q29820880](https://www.wikidata.org/wiki/Q29820880)  
**Source**: https://4ort.xyz/entity/hemipterous-dmel-cg4353


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q23977)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
5. [hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
7. [p38 MAPK signalling cascades: ancient roles and new functions](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977)
8. [Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
9. [CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
10. [Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977)
11. [Roles of the JNK signaling pathway in Drosophila morphogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977)
12. [hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977)
13. [p38 MAPK signalling cascades: ancient roles and new functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
14. [Roles of the JNK signaling pathway in Drosophila morphogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
15. [Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
16. [Signal strength and signal duration define two distinct aspects of JNK-regulated axon stability.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
17. [Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
18. [Protein kinases and phosphatases in the Drosophila genome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
19. [A sensitized PiggyBac-based screen for regulators of border cell migration in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977)
21. [The Drosophila serine protease homologue Scarface regulates JNK signalling in a negative-feedback loop during epithelial morphogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
22. [Planar polarity and actin dynamics in the epidermis of Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
23. [JNK signalling influences intracellular trafficking during Drosophila morphogenesis through regulation of the novel target gene Rab30.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
24. [Axon injury and regeneration in the adult Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
25. [Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
26. [Invasive cell behavior during Drosophila imaginal disc eversion is mediated by the JNK signaling cascade](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
27. [JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
28. [Drosophila Heat Shock Response Requires the JNK Pathway and Phosphorylation of Mixed Lineage Kinase at a Conserved Serine-Proline Motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
29. [JNK signaling in insulin-producing cells is required for adaptive responses to stress in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
30. [JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
31. [Regulation of a serine protease homolog by the JNK pathway during thoracic development ofDrosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
32. [The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
33. [Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
34. [Notch signaling through tramtrack bypasses the mitosis promoting activity of the JNK pathway in the mitotic-to-endocycle transition of Drosophila follicle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
35. [Control of metabolic homeostasis by stress signaling is mediated by the lipocalin NLaz.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
36. [Crystal cell rupture after injury in Drosophila requires the JNK pathway, small GTPases and the TNF homolog Eiger](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
37. [Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
38. [JNK signaling pathway required for wound healing in regenerating Drosophila wing imaginal discs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
39. [Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
40. [Draper acts through the JNK pathway to control synchronous engulfment of dying germline cells by follicular epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
41. [A directed screen for genes involved in Drosophila blood cell activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23977&geneProductId=UniProtKB:Q23977)
42. [D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
43. [A signaling network for patterning of neuronal connectivity in the Drosophila brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
44. [Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
45. [The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
46. [PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
47. [A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
48. [The PP2C Alphabet is a negative regulator of stress-activated protein kinase signaling in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
49. [A sensitized PiggyBac-based screen for regulators of border cell migration in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23977)
50. ensembl Release 106