# Hematopoietically expressed homeobox

> mammalian protein found in Mus musculus

**Wikidata**: [Q21428395](https://www.wikidata.org/wiki/Q21428395)  
**Source**: https://4ort.xyz/entity/hematopoietically-expressed-homeobox


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P43120)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
5. [Hhex is a direct repressor of endothelial cell-specific molecule 1 (ESM-1)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P43120&geneProductId=UniProtKB:P43120)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P43120&geneProductId=UniProtKB:P43120)
7. [Homeobox protein Hex induces SMemb/nonmuscle myosin heavy chain-B gene expression through the cAMP-responsive element](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
8. [The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
9. [Hhex is a direct repressor of endothelial cell-specific molecule 1 (ESM-1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P43120&geneProductId=UniProtKB:P43120)
12. [HEX expression and localization in normal mammary gland and breast carcinoma](http://www.ebi.ac.uk/QuickGO/annotations?protein=P43120&geneProductId=UniProtKB:P43120)
13. [Immunocytochemical characterization of murine Hex, a homeobox-containing protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P43120&geneProductId=UniProtKB:P43120)
14. [Immunocytochemical characterization of murine Hex, a homeobox-containing protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
15. [HEX expression and localization in normal mammary gland and breast carcinoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
16. [Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
17. [Homeobox gene Hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
18. [Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
19. [Correct patterning of the primitive streak requires the anterior visceral endoderm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
20. [HEX acts as a negative regulator of angiogenesis by modulating the expression of angiogenesis-related gene in endothelial cells in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
21. [Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function](http://www.ebi.ac.uk/QuickGO/annotations?protein=P43120&geneProductId=UniProtKB:P43120)
22. [HEX acts as a negative regulator of angiogenesis by modulating the expression of angiogenesis-related gene in endothelial cells in vitro](http://www.ebi.ac.uk/QuickGO/annotations?protein=P43120&geneProductId=UniProtKB:P43120)
23. [A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
24. [The homeobox gene HEX regulates proliferation and differentiation of hemangioblasts and endothelial cells during ES cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
25. [The homeoprotein Hex is required for hemangioblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
26. [The homeobox gene Hhex is essential for proper hepatoblast differentiation and bile duct morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
27. [Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
28. [The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
29. [An integrated regulatory network controlling survival and migration in thyroid organogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
30. [Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
31. [Impaired B cell development and function in mice with a targeted disruption of the homeobox gene Hex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
32. [Getting your head around Hex and Hesx1: forebrain formation in mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
33. [Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43120)
34. ensembl Release 106