# Hedgehog Dmel_CG4637

> protein found in Drosophila melanogaster

**Wikidata**: [Q29814574](https://www.wikidata.org/wiki/Q29814574)  
**Source**: https://4ort.xyz/entity/hedgehog-dmel-cg4637


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q02936)
3. Q20641742
4. [Regulation of Hedgehog signaling: a complex story](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
5. [In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
6. [The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
7. [The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
8. [The ihog cell-surface proteins bind Hedgehog and mediate pathway activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
9. [Genetic and biochemical definition of the Hedgehog receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
10. [Structure of a heparin-dependent complex of Hedgehog and Ihog](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
12. [The development of the Drosophila genital disc.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
14. [The development of the Drosophila genital disc.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
15. [The long-range activity of Hedgehog is regulated in the apical extracellular space by the glypican Dally and the hydrolase Notum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
16. [Cytoneme-mediated cell-cell contacts for Hedgehog reception.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
18. [In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
19. [Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
20. [Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
21. [Quantitative analysis of Hedgehog gradient formation using an inducible expression system](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
22. [Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
23. [Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
24. [Quantitative analysis of Hedgehog gradient formation using an inducible expression system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
25. [Patched, the receptor of Hedgehog, is a lipoprotein receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
26. [Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
27. [Secretion of the amino-terminal fragment of the hedgehog protein is necessary and sufficient for hedgehog signalling in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
28. [Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
29. [Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
30. [Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
31. [Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
32. [Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
33. [Coming to our senses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
34. [Bacterial Uracil Modulates Drosophila DUOX-Dependent Gut Immunity via Hedgehog-Induced Signaling Endosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
35. [Generating patterns from fields of cells. Examples from Drosophila segmentation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
36. [Cholesterol metabolism and embryogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
37. [Regulation of Hedgehog signaling: a complex story](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
38. [Sticking together and sorting things out: adhesion as a force in development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
39. [smoothened encodes a receptor-like serpentine protein required for hedgehog signalling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
40. [Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
41. [HMGCoA reductase potentiates hedgehog signaling in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
42. [Hedgehog acts as a somatic stem cell factor in the Drosophila ovary](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
43. [The evolution of arthropod segmentation mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
44. [Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
45. [Structure and expression of hedgehog, a Drosophila segment-polarity gene required for cell-cell communication](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
46. [Sticking together and sorting things out: adhesion as a force in development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
47. [Genetics of heart development.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
48. [Determination of cell fate along the anteroposterior axis of the Drosophila ventral midline.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)
49. [Branching morphogenesis of the Drosophila tracheal system.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02936&geneProductId=UniProtKB:Q02936)
50. [Hedgehog signaling patterns the tracheal branches](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02936)