# Heat shock protein family A (Hsp70) member 8

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5635988](https://www.wikidata.org/wiki/Q5635988)  
**Source**: https://4ort.xyz/entity/heat-shock-protein-family-a-hsp70-member-8


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P11142)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
5. [HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
6. [Identification and Characterization of a Novel Human Methyltransferase Modulating Hsp70 Protein Function through Lysine Methylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
7. [The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
8. [RING finger protein RNF207, a novel regulator of cardiac excitation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
9. [BAG-1 modulates the chaperone activity of Hsp70/Hsc70](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
10. [Histone deacetylase 10 promotes autophagy-mediated cell survival.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
11. [Distinct Roles of Molecular Chaperones HSP90α and HSP90β in the Biogenesis of KCNQ4 Channels](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
12. [Small glutamine-rich tetratricopeptide repeat-containing protein is composed of three structural units with distinct functions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
13. [The co-chaperone DNAJC12 binds to Hsc70 and is upregulated by endoplasmic reticulum stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
14. [Identification of Mrj, a DnaJ/Hsp40 family protein, as a keratin 8/18 filament regulatory protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
15. [Structural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70s](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
16. [The endoplasmic reticulum–associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3–dependent degradation of nascent CFTRΔF508](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
17. [The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
18. [Tetrameric Assembly of K(+) Channels Requires ER-Located Chaperone Proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
19. [Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
20. [Tid1 isoforms are mitochondrial DnaJ-like chaperones with unique carboxyl termini that determine cytosolic fate](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
21. [Molecularchaperones as HSF1-specific transcriptional repressors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
22. [ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
23. [A Novel ER J-protein DNAJB12 Accelerates ER-associated Degradation of Membrane Proteins Including CFTR](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
24. [ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
25. [Binding of Human Nucleotide Exchange Factors to Heat Shock Protein 70 (Hsp70) Generates Functionally Distinct Complexes in Vitro](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
26. [A Product of the Human Gene Adjacent to parkin Is a Component of Lewy Bodies and Suppresses Pael Receptor-induced Cell Death](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
27. [Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
28. [Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
29. [CHIP participates in protein triage decisions by preferentially ubiquitinating Hsp70-bound substrates](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
30. [Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
31. [Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
32. [Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
33. [Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
34. [Metazoan Hsp70 machines use Hsp110 to power protein disaggregation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
35. [A human protein-protein interaction network: a resource for annotating the proteome](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
36. [Identification and comparative analysis of hepatitis C virus-host cell protein interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
37. [Dynamic protein-protein interaction wiring of the human spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
38. [Streamline proteomic approach for characterizing protein-protein interaction network in a RAD52 protein complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
39. [Analysis of proteins copurifying with the CD4/lck complex using one-dimensional polyacrylamide gel electrophoresis and mass spectrometry: comparison with affinity-tag based protein detection and evaluation of different solubilization methods](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
40. [A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
41. [Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
42. [CHIP interacts with heat shock factor 1 during heat stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
43. [Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
44. [Functional specialization of beta-arrestin interactions revealed by proteomic analysis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
45. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
46. [Identification of potential protein interactors of Lrrk2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
47. [Interplay of LRRK2 with chaperone-mediated autophagy](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
48. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
49. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)
50. [The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11142&geneProductId=UniProtKB:P11142)