# Heat shock protein family A (Hsp70) member 5

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116494](https://www.wikidata.org/wiki/Q21116494)  
**Source**: https://4ort.xyz/entity/heat-shock-protein-family-a-hsp70-member-5-q21116494


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P11021)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
5. [Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
6. [Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
7. [ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11021&geneProductId=UniProtKB:P11021)
9. [ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11021&geneProductId=UniProtKB:P11021)
10. [Identification and characterization of interactions between abscisic acid and human heat shock protein 70 family members](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11021&geneProductId=UniProtKB:P11021)
11. [The Salmonella type III secretion effector, salmonella leucine-rich repeat protein (SlrP), targets the human chaperone ERdj3](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11021&geneProductId=UniProtKB:P11021)
12. [Role of the lectin VIP36 in post-ER quality control of human alpha1-antitrypsin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
13. [GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
14. [A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
15. [Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
16. [OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
17. [Unraveling the Role of KIAA1199, a Novel Endoplasmic Reticulum Protein, in Cancer Cell Migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
18. [ERdj5 Is the ER Reductase that Catalyzes the Removal of Non-Native Disulfides and Correct Folding of the LDL Receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
19. [Dimerization of pro-oncogenic protein Anterior Gradient 2 is required for the interaction with BiP/GRP78](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
20. [A novel link between Fic (filamentation induced by cAMP)-mediated adenylylation/AMPylation and the unfolded protein response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
21. [Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
22. [GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
23. [The Salmonella type III secretion effector, salmonella leucine-rich repeat protein (SlrP), targets the human chaperone ERdj3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
24. [Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
25. [Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
26. [Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
27. [IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
28. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
29. [BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
30. [Identification of a potential tumor differentiation factor receptor candidate in prostate cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
31. [Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
32. [Regulated release of ERdj3 from unfolded proteins by BiP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
33. [Dermokine-β impairs ERK signaling through direct binding to GRP78](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
34. [The tumor suppressor Par-4 activates an extrinsic pathway for apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
35. [Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
36. [Identification and Characterization of a Novel Human Methyltransferase Modulating Hsp70 Protein Function through Lysine Methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
37. [Calreticulin binds hYRNA and the 52-kDa polypeptide component of the Ro/SS-A ribonucleoprotein autoantigen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
38. [Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11021&geneProductId=UniProtKB:P11021)
39. [Roles of CHOP/GADD153 in endoplasmic reticulum stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11021&geneProductId=UniProtKB:P11021)
40. [The unfolded protein response: integrating stress signals through the stress sensor IRE1α](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11021&geneProductId=UniProtKB:P11021)
41. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11021&geneProductId=UniProtKB:P11021)
42. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
43. [Identification and characterization of interactions between abscisic acid and human heat shock protein 70 family members](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
44. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
45. [The unfolded protein response: integrating stress signals through the stress sensor IRE1α](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
46. [Roles of CHOP/GADD153 in endoplasmic reticulum stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
47. [ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)
48. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11021&geneProductId=UniProtKB:P11021)
49. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11021&geneProductId=UniProtKB:P11021)
50. [WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11021)