# Heat shock protein family A (Hsp70) member 1A

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21118347](https://www.wikidata.org/wiki/Q21118347)  
**Source**: https://4ort.xyz/entity/heat-shock-protein-family-a-hsp70-member-1a


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P0DMV9)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
5. [HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
6. [The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
7. [Identification and Characterization of a Novel Human Methyltransferase Modulating Hsp70 Protein Function through Lysine Methylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
8. [BAG5 inhibits parkin and enhances dopaminergic neuron degeneration](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
9. [Histone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
10. [RING finger protein RNF207, a novel regulator of cardiac excitation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
11. [ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
12. [Binding of Human Nucleotide Exchange Factors to Heat Shock Protein 70 (Hsp70) Generates Functionally Distinct Complexes in Vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
13. [Interactions between Hsp70 and the hydrophobic core of alpha-synuclein inhibit fibril assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
14. [A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
15. [A novel nuclear DnaJ protein, DNAJC8, can suppress the formation of spinocerebellar ataxia 3 polyglutamine aggregation in a J-domain independent manner.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
16. [HSP70 regulates the function of mitotic centrosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
17. [Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
18. [ChChd3, an Inner Mitochondrial Membrane Protein, Is Essential for Maintaining Crista Integrity and Mitochondrial Function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
19. [Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
20. [Systematic protein-protein interaction mapping for clinically relevant human GPCRs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
21. [BAG5 inhibits parkin and enhances dopaminergic neuron degeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
22. [Identification and Characterization of a Novel Human Methyltransferase Modulating Hsp70 Protein Function through Lysine Methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
23. [The Molecular Chaperone HSP70 Binds to and Stabilizes NOD2, an Important Protein Involved in Crohn Disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
24. [CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
25. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
26. [CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
27. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
28. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
29. [Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
30. [Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
31. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
32. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
33. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
34. [The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
35. [HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
36. [Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
37. [Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
38. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
39. [Control of mRNA decay by heat shock-ubiquitin-proteasome pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
40. [Stress-induced localization of HSPA6 (HSP70B′) and HSPA1A (HSP70-1) proteins to centrioles in human neuronal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
41. [Control of mRNA decay by heat shock-ubiquitin-proteasome pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
42. [Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
43. [Chaperone hsp27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
44. [The Molecular Chaperone HSP70 Binds to and Stabilizes NOD2, an Important Protein Involved in Crohn Disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
45. [Stress-induced localization of HSPA6 (HSP70B′) and HSPA1A (HSP70-1) proteins to centrioles in human neuronal cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
46. [TRIM37 defective in mulibrey nanism is a novel RING finger ubiquitin E3 ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P0DMV9)
47. [Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
48. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
49. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)
50. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P0DMV9&geneProductId=UniProtKB:P0DMV9)