# HCLS1 associated protein X-1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21107292](https://www.wikidata.org/wiki/Q21107292)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/HAX1)  
**Source**: https://4ort.xyz/entity/hcls1-associated-protein-x-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O00165)
3. Q20641742
4. [Evidence that HAX-1 is an interleukin-1 alpha N-terminal binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
5. [Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
6. [Molecular interaction between HAX-1 and XIAP inhibits apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
7. [RAC3 is a pro-migratory co-activator of ERα](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
8. [hSav1 interacts with HAX1 and attenuates its anti-apoptotic effects in MCF-7 breast cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
9. [Pelota interacts with HAX1, EIF3G and SRPX and the resulting protein complexes are associated with the actin cytoskeleton](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
10. [The classical swine fever virus N-terminal protease N(pro) binds to cellular HAX-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
11. [Grb7 binds to Hax‐1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
12. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
13. [Hax-1 identified as a two-pore channel (TPC)-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
14. [Screening of binding proteins that interact with human Salvador 1 in a human fetal liver cDNA library by the yeast two-hybrid system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
15. [Intracellular IL-1alpha-binding proteins contribute to biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
17. [HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
18. [Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
19. [Oxidative Stress-Induced Signaling Pathways Implicated in the Pathogenesis of Parkinson’s Disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00165)
20. [Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00165&geneProductId=UniProtKB:O00165)
21. Ensembl Release 99