# GUIDES: sgRNA design for loss-of-function screens

> Research article (Nature Methods, 2017) · cited 97× · AI/ML

**Wikidata**: [openalex:W2951484233](https://www.wikidata.org/wiki/openalex:W2951484233)  
**Source**: https://4ort.xyz/entity/guides-sgrna-design-for-loss-of-function-screens