Growth hormone releasing hormone receptor
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P129
  value: tesamorelin
additional property: PropertyValue
  property ID: P361
  value: GPCR, family 2, growth hormone-releasing hormone receptor
additional property: PropertyValue
  property ID: P361
  value: GPCR family 2, extracellular hormone receptor domain superfamily
additional property: PropertyValue
  property ID: P361
  value: GPCR, family 2, secretin-like
additional property: PropertyValue
  property ID: P527
  value: GPCR, family 2, extracellular hormone receptor domain
additional property: PropertyValue
  property ID: P527
  value: GPCR, family 2, secretin-like, conserved site
additional property: PropertyValue
  property ID: P527
  value: GPCR, family 2-like
additional property: PropertyValue
  property ID: P637
  value: NP_000814
additional property: PropertyValue
  property ID: P638
  value: 2XDG
additional property: PropertyValue
  property ID: P680
  value: G protein-coupled receptor activity
additional property: PropertyValue
  property ID: P680
  value: growth factor binding
additional property: PropertyValue
  property ID: P680
  value: signal transducer activity
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: adenylate cyclase-activating G protein-coupled receptor signaling pathway
additional property: PropertyValue
  property ID: P682
  value: determination of adult lifespan
additional property: PropertyValue
  property ID: P682
  value: adenylate cyclase-modulating G protein-coupled receptor signaling pathway
additional property: PropertyValue
  property ID: P692
  value: PBB GE GHRHR 207825 s at fs.png
additional property: PropertyValue
  property ID: P702
  value: GHRHR
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000320180
additional property: PropertyValue
  property ID: P705
  value: ENSP00000338184
additional property: PropertyValue
  property ID: P705
  value: ENSP00000379529
additional property: PropertyValue
  property ID: P2888
  value: http://purl.uniprot.org/uniprot/Q02643
additional property: PropertyValue
  property ID: P7260
  value: 9.A.14.4.7
confidence:
  popularity graph score:
    score: 0.003
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 21
      unique citations norm: 0.008
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 21
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P129:
    value: Q7705415
    source count: 1
    confidence: 0.2
    value label: tesamorelin
  P352:
    value: Q02643
    source count: 1
    confidence: 0.2
  P361:
    value: Q24773175
    source count: 1
    confidence: 0.2
    value label: GPCR, family 2, growth hormone-releasing hormone receptor
  P361:
    value: Q41797557
    source count: 1
    confidence: 0.2
    value label: GPCR family 2, extracellular hormone receptor domain superfamily
  P361:
    value: Q7444439
    source count: 1
    confidence: 0.2
    value label: GPCR, family 2, secretin-like
  P361:
    value: Q38173
    source count: 1
    confidence: 0.2
    value label: G protein-coupled recepteishon
  P361:
    value: Q83137599
    source count: 1
    confidence: 0.2
    value label: GPCR, family 2, extracellular hormone receptor domain, protein family
  P527:
    value: Q24741953
    source count: 1
    confidence: 0.2
    value label: GPCR, family 2, extracellular hormone receptor domain
  P527:
    value: Q24774228
    source count: 1
    confidence: 0.2
    value label: GPCR, family 2, secretin-like, conserved site
  P527:
    value: Q24766813
    source count: 1
    confidence: 0.2
    value label: GPCR, family 2-like
  P637:
    value: NP_000814
    source count: 1
    confidence: 0.2
  P638:
    value: 2XDG
    source count: 1
    confidence: 0.2
  P680:
    value: Q14859545
    source count: 3
    confidence: 0.6
    value label: G protein-coupled receptor activity
  P680:
    value: Q14877469
    source count: 1
    confidence: 0.2
    value label: growth factor binding
  P680:
    value: Q14820643
    source count: 1
    confidence: 0.2
    value label: signal transducer activity
  P680:
    value: Q14875276
    source count: 2
    confidence: 0.4
    value label: peptide hormone binding
  P680:
    value: Q167149
    source count: 2
    confidence: 0.4
    value label: protein binding
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q14327652
    source count: 4
    confidence: 0.8
    value label: integral component of membrane
  P681:
    value: Q14349455
    source count: 2
    confidence: 0.4
    value label: membrane

value: Q906755
source count: 1
confidence: 0.2
value label: nuclear matrix

value: Q29548
source count: 4
confidence: 0.8
value label: plasma membrane

value: Q14860468
source count: 3
confidence: 0.6
value label: adenylate cyclase-activating G protein-coupled receptor signaling pathway

value: Q14818034
source count: 1
confidence: 0.2
value label: determination of adult lifespan

value: Q14821396
source count: 1
confidence: 0.2
value label: adenylate cyclase-modulating G protein-coupled receptor signaling pathway

value: Q14820897
source count: 1
confidence: 0.2
value label: response to glucocorticoid

value: Q14859575
source count: 1
confidence: 0.2
value label: cell maturation

value: PBB GE GHRHR 207825 s at fs.png
source count: 0
confidence: 0.0

value: Q15318729
source count: 1
confidence: 0.2
value label: GHRHR

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000320180
source count: 1
confidence: 0.2

value: ENSP00000338184
source count: 1
confidence: 0.2

value: ENSP00000379529
source count: 1
confidence: 0.2

value: ENSP00000386602
source count: 1
confidence: 0.2

value: ENSP00000387113
source count: 1
confidence: 0.2

value: http://purl.uniprot.org/uniprot/Q02643
source count: 1
confidence: 0.2

value: 9.A.14.4.7
source count: 2
confidence: 0.4

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Molecular cloning and expression of a human anterior pituitary receptor for growth hormone-releasing hormone
stated in qid: Q24337726
retrieved: 2019-04-08

source: Molecular cloning and expression of a human anterior pituitary receptor for growth hormone-releasing hormone
stated in qid: Q24337726
retrieved: 2018-07-16

source: GOA
stated in qid: Q28018111
retrieved: 2018-01-31

source: Molecular cloning and expression of a pituitary-specific receptor for growth hormone-releasing hormone
stated in qid: Q24337590
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Restricted presence of the growth hormone-releasing hormone receptor to somatotropes in rat and human pituitaries
stated in qid: Q22003822
retrieved: 2019-04-08

source: Structure and regulation of the human growth hormone-releasing hormone receptor gene
stated in qid: Q24313531
retrieved: 2019-04-08

source: Heterozygosity for a mutation in the growth hormone-releasing hormone receptor gene does not influence adult stature, but affects body composition
stated in qid: Q24300014
retrieved: 2019-04-08

source: Expression of a splice variant of the receptor for GHRH in 3T3 fibroblasts activates cell proliferation responses to GHRH analogs
stated in qid: Q24292089
retrieved: 2019-04-08

source: Ligand-dependent and -independent effects of splice variant 1 of growth hormone-releasing hormone receptor
stated in qid: Q24309176
retrieved: 2018-07-16

source: Nonsense mutation in the human growth hormone-releasing hormone receptor causes growth failure analogous to the little (lit) mouse
stated in qid: Q24311677
retrieved: 2019-04-08

source: Cellular distribution of growth hormone-releasing hormone receptor in human reproductive system and breast and prostate cancers
stated in qid: Q24304995
retrieved: 2019-04-08

source: Ligand-dependent and -independent effects of splice variant 1 of growth hormone-releasing hormone receptor
stated in qid: Q24309176
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: IUPHAR/BPS Guide to PHARMACOLOGY
stated in qid: Q17091219
retrieved: 2016-08-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

source: Identifiers.org
stated in qid: Q16335166

wikidata id: Q5611730
domain: protein
level: standard
html url: https://4ort.xyz/entity/growth-hormone-releasing-hormone-receptor-q5611730
markdown url: https://4ort.xyz/entity/growth-hormone-releasing-hormone-receptor-q5611730.md
facts url summary: https://4ort.xyz/entity/growth-hormone-releasing-hormone-receptor-q5611730/facts.json
facts url standard: https://4ort.xyz/entity/growth-hormone-releasing-hormone-receptor-q5611730/facts.json
facts url full: https://4ort.xyz/entity/growth-hormone-releasing-hormone-receptor-q5611730/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-01T16:39:43.979065Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:22:15.493125+00:00Z