# Growth hormone receptor

> a protein involved in the binding of the growth hormone

**Wikidata**: [Q2299608](https://www.wikidata.org/wiki/Q2299608)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Growth_hormone_receptor)  
**Source**: https://4ort.xyz/entity/growth-hormone-receptor


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P10912)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P16882)
4. Q20641742
5. Freebase Data Dumps. 2013
6. [Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
7. [A single amino acid substitution in the exoplasmic domain of the human growth hormone (GH) receptor confers familial GH resistance (Laron syndrome) with positive GH-binding activity by abolishing receptor homodimerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
8. [Human growth hormone and extracellular domain of its receptor: crystal structure of the complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
9. [A Membrane-Fixed, Truncated Isoform of the Human Growth Hormone Receptor1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912)
10. [Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912)
11. [Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912)
12. [Human growth hormone and extracellular domain of its receptor: crystal structure of the complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912)
13. [Growth hormone receptor and serum binding protein: purification, cloning and expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912)
14. [Large-scale structural analysis of the classical human protein tyrosine phosphatome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
15. [Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
16. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
17. [A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
18. [Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
19. [Structural Plasticity in a Remodeled Protein-Protein Interface](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
20. [The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
21. [Growth hormone promotes the association of transcription factor STAT5 with the growth hormone receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16882)
22. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912)
23. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16882&geneProductId=UniProtKB:P16882)
24. [Growth hormone receptor and serum binding protein: purification, cloning and expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
25. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
26. [Model for growth hormone receptor activation based on subunit rotation within a receptor dimer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
27. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
28. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16882)
29. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16882)
30. [Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
31. [Up-regulation of GH-binding protein by mouse GH in transgenic mice overexpressing GH-releasing hormone](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16882&geneProductId=UniProtKB:P16882)
32. [Hepatic Binding of Human and Bovine Growth Hormones and Ovine Prolactin in the Dwarf “Little” Mouse*](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16882&geneProductId=UniProtKB:P16882)
33. [Hepatic Binding of Human and Bovine Growth Hormones and Ovine Prolactin in the Dwarf “Little” Mouse*](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16882)
34. [Up-regulation of GH-binding protein by mouse GH in transgenic mice overexpressing GH-releasing hormone](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16882)
35. [A single amino acid substitution in the exoplasmic domain of the human growth hormone (GH) receptor confers familial GH resistance (Laron syndrome) with positive GH-binding activity by abolishing receptor homodimerization](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912)
36. [Structurally distinct membrane-associated and soluble forms of GH-binding protein in the mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16882)
37. [Functional growth hormone (GH) receptors and GH are expressed by preimplantation mouse embryos: a role for GH in early embryogenesis?](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16882&geneProductId=UniProtKB:P16882)
38. [Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16882&geneProductId=UniProtKB:P16882)
39. [Functional growth hormone (GH) receptors and GH are expressed by preimplantation mouse embryos: a role for GH in early embryogenesis?](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16882)
40. [Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16882)
41. [Mutations of the growth hormone receptor in children with idiopathic short stature. The Growth Hormone Insensitivity Study Group](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
42. [Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912)
43. [Mutations of the growth hormone receptor in children with idiopathic short stature. The Growth Hormone Insensitivity Study Group](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912)
44. [Characterization of the human growth hormone receptor gene and demonstration of a partial gene deletion in two patients with Laron-type dwarfism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912)
45. [Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16882&geneProductId=UniProtKB:P16882)
46. [Growth hormone promotes the association of transcription factor STAT5 with the growth hormone receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16882&geneProductId=UniProtKB:P16882)
47. [Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16882)
48. Ensembl Release 99
49. ensembl Release 106
50. Quora