# Groucho Dmel_CG8384

> protein found in Drosophila melanogaster

**Wikidata**: [Q29817921](https://www.wikidata.org/wiki/Q29817921)  
**Source**: https://4ort.xyz/entity/groucho-dmel-cg8384


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P16371)
3. Q20641742
4. [Two modes of recruitment of E(spl) repressors onto target genes.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
5. [Transcriptional repression: the long and the short of it](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
6. [Runt and Lozenge function in Drosophila development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
7. [Structure, function and evolution of sex-determining systems in Dipteran insects](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
8. [Transcriptional coregulators in development.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
9. [Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
10. [Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
11. [Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
12. [The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
13. [Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
14. [Degringolade, a SUMO-targeted ubiquitin ligase, inhibits Hairy/Groucho-mediated repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
15. [Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
16. [A network of interacting transcriptional regulators involved in Drosophila neural fate specification revealed by the yeast two-hybrid system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
17. [Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
18. [Hedgehog restricts its expression domain in the Drosophila wing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
19. [A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
20. [A protein interaction map of Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
21. [Dorsal-mediated repression requires the formation of a multiprotein repression complex at the ventral silencer.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
22. [Partner specificity is essential for proper function of the SIX-type homeodomain proteins Sine oculis and Optix during fly eye development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
23. [Huckebein repressor activity in Drosophila terminal patterning is mediated by Groucho](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
24. [The Drosophila Nkx6 homeodomain protein has both activation and repression domains and can activate target gene expression.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
25. [Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
26. [Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
27. [Transcriptional coregulators in development.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
28. [Two modes of recruitment of E(spl) repressors onto target genes.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
29. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
30. [Cell fate specification in the Drosophila retina](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
31. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
32. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
33. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
34. [Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryo](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
35. [Origins of context-dependent gene repression by capicua](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
36. [The Enhancer of split complex and adjacent genes in the 96F region of Drosophila melanogaster are required for segregation of neural and epidermal progenitor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
37. [Structure, function and evolution of sex-determining systems in Dipteran insects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
38. [Hedgehog restricts its expression domain in the Drosophila wing](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
39. [A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16371&geneProductId=UniProtKB:P16371)
40. [Origins of context-dependent gene repression by capicua](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
41. [Phosphorylation of Groucho Mediates RTK Feedback Inhibition and Prolonged Pathway Target Gene Expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
42. [Multiple RTK pathways downregulate Groucho-mediated repression in Drosophila embryogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
43. [The SUMO-targeted ubiquitin ligase, Dgrn, is essential for Drosophila innate immunity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16371)
44. ensembl Release 106