# GNAS complex locus

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q39627001](https://www.wikidata.org/wiki/Q39627001)  
**Source**: https://4ort.xyz/entity/gnas-complex-locus-q39627001


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P63095)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
6. [Two overlapping reading frames in a single exon encode interacting proteins--a novel way of gene usage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
7. [Enhancement of AG1024-induced H9c2 cardiomyoblast cell apoptosis via the interaction of IGF2R with Galpha proteins and its downstream PKA and PLC-beta modulators by IGF-II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
8. [Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
9. [Interaction of alpha1-syntrophin with multiple isoforms of heterotrimeric G protein alpha subunits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
10. [Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
11. [Functional characterization of heterotrimeric G-proteins in rat diaphragm muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
12. [Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Specific activation of Gsalpha by an NDPK B.Gbetagamma complex in H10 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
13. [Assembly of a beta2-adrenergic receptor--GluR1 signalling complex for localized cAMP signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
14. [Rosiglitazone restores renal D1A receptor-Gs protein coupling by reducing receptor hyperphosphorylation in obese rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
15. [Ultra-low dose naloxone restores the antinociceptive effect of morphine in pertussis toxin-treated rats by reversing the coupling of mu-opioid receptors from Gs-protein to coupling to Gi-protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
16. [Gbetagamma that interacts with adenylyl cyclase in opioid tolerance originates from a Gs protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
17. [G protein betagamma subunits interact with alphabeta- and gamma-tubulin and play a role in microtubule assembly in PC12 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
18. [The heterotrimeric G protein subunits Gαq and Gβ1 have lysophospholipase D activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
19. [Sex differences in corticotropin-releasing factor receptor signaling and trafficking: potential role in female vulnerability to stress-related psychopathology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q792G6)
21. [Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q792G6)
22. [Functional characterization of heterotrimeric G-proteins in rat diaphragm muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q792G6)
23. [G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
24. [Glucagon-mediated internalization of serine-phosphorylated glucagon receptor and Gsalpha in rat liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
25. [A proline-rich region and nearby cysteine residues target XLalphas to the Golgi complex region](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
26. [Treatment with atorvastatin partially protects the rat heart from harmful catecholamine effects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
27. [VIP Induces the Translocation and Degradation of the Subunit of Gs Protein in Rat Pituitary GH4C1 Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
28. [Live cell imaging of Gs and the beta2-adrenergic receptor demonstrates that both alphas and beta1gamma7 internalize upon stimulation and exhibit similar trafficking patterns that differ from that of the beta2-adrenergic receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
29. [Functional reconstitution of G-protein-coupled receptor-mediated adenylyl cyclase activation by a baculoviral co-display system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
30. [Partial rescue of functional interactions of a nonpalmitoylated mutant of the G-protein G alpha s by fusion to the beta-adrenergic receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
31. [Peripheral projections of NESP55 containing neurons in the rat sympathetic ganglia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
32. [Chronic treatment with escitalopram but not R-citalopram translocates Galpha(s) from lipid raft domains and potentiates adenylyl cyclase: a 5-hydroxytryptamine transporter-independent action of this antidepressant compound](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
33. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q792G6)
34. [Live cell imaging of Gs and the beta2-adrenergic receptor demonstrates that both alphas and beta1gamma7 internalize upon stimulation and exhibit similar trafficking patterns that differ from that of the beta2-adrenergic receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q792G6)
35. [Glucagon-mediated internalization of serine-phosphorylated glucagon receptor and Gsalpha in rat liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q792G6)
36. [Partial rescue of functional interactions of a nonpalmitoylated mutant of the G-protein G alpha s by fusion to the beta-adrenergic receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q792G6)
37. [G-protein-coupled receptor signaling components localize in both sarcolemmal and intracellular caveolin-3-associated microdomains in adult cardiac myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q792G6)
38. [Transgenic overexpression of the extra-large Gsα variant XLαs enhances Gsα-mediated responses in the mouse renal proximal tubule in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
39. [Antagonist minigenes identify genes regulated by parathyroid hormone through G protein-selective and G protein co-regulated mechanisms in osteoblastic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
40. [Alterations in hepatic glucagon receptor density and in Gsalpha and Gialpha2 protein content with diet-induced hepatic steatosis: effects of acute exercise](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
41. [Indomethacin enhances shuttling of aquaporin-2 despite decreased abundance in rat kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
42. [Conditional overexpression of the wild-type Gs alpha as the gsp oncogene initiates chronic extracellularly regulated kinase 1/2 activation and hormone hypersecretion in pituitary cell lines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
43. [Modulation of rat cardiac sodium channel by the stimulatory G protein alpha subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
44. [Functional selectivity of central Gα-subunit proteins in mediating the cardiovascular and renal excretory responses evoked by central α(2) -adrenoceptor activation in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
45. [G(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63095)
46. [Alterations in hepatic glucagon receptor density and in Gsalpha and Gialpha2 protein content with diet-induced hepatic steatosis: effects of acute exercise](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q792G6)
47. ensembl Release 104