# Glycogen synthase kinase 3 beta

> mammalian protein found in Mus musculus

**Wikidata**: [Q21983050](https://www.wikidata.org/wiki/Q21983050)  
**Source**: https://4ort.xyz/entity/glycogen-synthase-kinase-3-beta


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WV60&geneProductId=UniProtKB:Q9WV60)
5. [The costimulation-regulated duration of PKB activation controls T cell longevity](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WV60&geneProductId=UniProtKB:Q9WV60)
6. [PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
7. [Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
8. [GSK3beta positively regulates Hedgehog signaling through Sufu in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
9. [DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
10. [An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
11. [ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
12. [Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
13. [Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
14. [Protein kinase CKII regulates the interaction of beta-catenin with alpha-catenin and its protein stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
15. [Functional Interaction of an Axin Homolog, Conductin, with β-Catenin, APC, and GSK3β](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
16. [SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
17. [Frat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3β subcellular localization in pluripotent cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
18. [Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
19. [DISC1-dependent switch from progenitor proliferation to migration in the developing cortex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
20. [Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
21. [Epm2a suppresses tumor growth in an immunocompromised host by inhibiting Wnt signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
22. [Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
23. [LRP5 in premature adrenarche and in metabolic characteristics of prepubertal children](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
24. [Glycogen synthase kinase-3 plays a central role in mediating glucocorticoid-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
25. [Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
26. [Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
27. [SRF Phosphorylation by Glycogen Synthase Kinase-3 Promotes Axon Growth in Hippocampal Neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
28. [F-box protein FBXL19–mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
29. [Wnt5a modulates glycogen synthase kinase 3 to induce phosphorylation of receptor tyrosine kinase Ror2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
30. [The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
31. [LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
32. [GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
33. [The costimulation-regulated duration of PKB activation controls T cell longevity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
34. [Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
35. [Mitotic clonal expansion: a synchronous process required for adipogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
36. [Spatially Coordinated Kinase Signaling Regulates Local Axon Degeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
37. [Light and electron microscopy study of glycogen synthase kinase-3beta in the mouse brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
38. [Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
39. [Mitotic clonal expansion: a synchronous process required for adipogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WV60&geneProductId=UniProtKB:Q9WV60)
40. [Functional domains of axin. Importance of the C terminus as an oligomerization domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
41. [Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
42. [Insulin and wnt1 pathways cooperate to induce reserve cell activation in differentiation and myotube hypertrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
43. [CRMP2 tethers kainate receptor activity to cytoskeleton dynamics during neuronal maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
44. [Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
45. [Identification of zinc-finger BED domain-containing 3 (Zbed3) as a novel Axin-interacting protein that activates Wnt/beta-catenin signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
46. [Mitotic phosphorylation of tankyrase, a PARP that promotes spindle assembly, by GSK3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
47. [Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WV60&geneProductId=UniProtKB:Q9WV60)
48. [Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)
49. [F-box protein FBXL19–mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WV60&geneProductId=UniProtKB:Q9WV60)
50. [Hepatocyte Growth Factor Modulates Interleukin-6 Production in Bone Marrow Derived Macrophages: Implications for Inflammatory Mediated Diseases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WV60)