# Glycine receptor, alpha 1 subunit

> mammalian protein found in Mus musculus

**Wikidata**: [Q21983316](https://www.wikidata.org/wiki/Q21983316)  
**Source**: https://4ort.xyz/entity/glycine-receptor-alpha-1-subunit


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q64018)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64018&geneProductId=UniProtKB:Q64018)
5. [The frameshift mutation oscillator (Glra1(spd-ot)) produces a complete loss of glycine receptor alpha1-polypeptide in mouse central nervous system](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64018&geneProductId=UniProtKB:Q64018)
6. [Point mutation of glycine receptor alpha 1 subunit in the spasmodic mouse affects agonist responses](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64018&geneProductId=UniProtKB:Q64018)
7. [A frameshift mutation in the mouse alpha 1 glycine receptor gene (Glra1) results in progressive neurological symptoms and juvenile death](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64018&geneProductId=UniProtKB:Q64018)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
9. [Altered sedative effects of ethanol in mice with α1 glycine receptor subunits that are insensitive to Gβγ modulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64018&geneProductId=UniProtKB:Q64018)
10. [Distinct physiological mechanisms underlie altered glycinergic synaptic transmission in the murine mutants spastic, spasmodic, and oscillator](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64018&geneProductId=UniProtKB:Q64018)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
12. [Point mutation of glycine receptor alpha 1 subunit in the spasmodic mouse affects agonist responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
13. [The frameshift mutation oscillator (Glra1(spd-ot)) produces a complete loss of glycine receptor alpha1-polypeptide in mouse central nervous system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
14. [A frameshift mutation in the mouse alpha 1 glycine receptor gene (Glra1) results in progressive neurological symptoms and juvenile death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
15. [Altered sedative effects of ethanol in mice with α1 glycine receptor subunits that are insensitive to Gβγ modulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
16. [Distinct physiological mechanisms underlie altered glycinergic synaptic transmission in the murine mutants spastic, spasmodic, and oscillator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
17. [Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
18. [Hyperekplexia phenotype of glycine receptor alpha1 subunit mutant mice identifies Zn(2+) as an essential endogenous modulator of glycinergic neurotransmission](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64018&geneProductId=UniProtKB:Q64018)
19. [Nmf11 is a novel ENU-induced mutation in the mouse glycine receptor alpha 1 subunit](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64018&geneProductId=UniProtKB:Q64018)
20. [Isoform-selective deficit of glycine receptors in the mouse mutant spastic](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
21. [Hyperekplexia phenotype of glycine receptor alpha1 subunit mutant mice identifies Zn(2+) as an essential endogenous modulator of glycinergic neurotransmission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
22. [Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
23. [A novel glycine receptor beta subunit splice variant predicts an unorthodox transmembrane topology. Assembly into heteromeric receptor complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64018&geneProductId=UniProtKB:Q64018)
24. [A novel glycine receptor beta subunit splice variant predicts an unorthodox transmembrane topology. Assembly into heteromeric receptor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
25. [Nmf11 is a novel ENU-induced mutation in the mouse glycine receptor alpha 1 subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
26. [Increased sensitization of acoustic startle response in spasmodic mice with a mutation of the glycine receptor alpha1-subunit gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
27. [Effects of functional knock-out of alpha 1 glycine-receptors on breathing movements in oscillator mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
28. [Genetic mapping and evaluation of candidate genes for spasmodic, a neurological mouse mutation with abnormal startle response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
29. [Increased startle responses in mice carrying mutations of glycine receptor subunit genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
30. [Phenotypic heterogeneity and disease course in three murine strains with mutations in genes encoding for alpha 1 and beta glycine receptor subunits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
31. [The respiratory rhythm in mutant oscillator mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
32. [Calcium-regulated potassium currents secure respiratory rhythm generation after loss of glycinergic inhibition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
33. [The zona pellucida-initiated acrosome reaction: defect due to mutations in the sperm glycine receptor/Cl(-) channel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
34. [Altered inhibitory synaptic transmission in superficial dorsal horn neurones in spastic and oscillator mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64018&geneProductId=UniProtKB:Q64018)
35. [Altered inhibitory synaptic transmission in superficial dorsal horn neurones in spastic and oscillator mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64018)
36. ensembl Release 106