# glutathione peroxidase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21157938](https://www.wikidata.org/wiki/Q21157938)  
**Source**: https://4ort.xyz/entity/glutathione-peroxidase-1


## References

1. UniProt
2. [BioGRID](https://thebiogrid.org/news/227)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P07203)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07203&geneProductId=UniProtKB:P07203)
6. [Glutathione peroxidase 1 is regulated by the c-Abl and Arg tyrosine kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
7. [Overexpression of cytosolic glutathione peroxidase (GPX1) delays endothelial cell growth and increases resistance to toxic challenges](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07203&geneProductId=UniProtKB:P07203)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
10. [Overexpression of cytosolic glutathione peroxidase (GPX1) delays endothelial cell growth and increases resistance to toxic challenges](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
11. [Mitochondrial GPx1 decreases induced but not basal oxidative damage to mtDNA in T47D cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
12. [Cellular glutathione peroxidase in human brain: cellular distribution, and its potential role in the degradation of Lewy bodies in Parkinson's disease and dementia with Lewy bodies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
13. [Mitochondrial GPx1 decreases induced but not basal oxidative damage to mtDNA in T47D cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07203&geneProductId=UniProtKB:P07203)
14. [Modulation of the chymotrypsin-like activity of the 20S proteasome by intracellular redox status: effects of glutathione peroxidase-1 overexpression and antioxidant drugs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
15. [Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07203&geneProductId=UniProtKB:P07203)
16. [Glutathione peroxidase-1 protects from CD95-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
17. [Overexpression of human GPX1 modifies Bax to Bcl-2 apoptotic ratio in human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
18. [Gene x Gene interaction between MnSOD and GPX-1 and breast cancer risk: a nested case-control study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
19. [Glutathione peroxidase-1 inhibits UVA-induced AP-2alpha expression in human keratinocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
20. [GPx-1 modulates Akt and P70S6K phosphorylation and Gadd45 levels in MCF-7 cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07203&geneProductId=UniProtKB:P07203)
21. [Glutathione Peroxidase 1 Activity and Cardiovascular Events in Patients with Coronary Artery Disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
22. [Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
23. [GPx-1 modulates Akt and P70S6K phosphorylation and Gadd45 levels in MCF-7 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07203)
24. Ensembl Release 99
25. UMLS 2023