Glutathione peroxidase 1
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P04041
additional property: PropertyValue
  property ID: P361
  value: Thioredoxin-like superfamily
additional property: PropertyValue
  property ID: P361
  value: glutathione peroxidase
additional property: PropertyValue
  property ID: P361
  value: Glutathione peroxidase active site, protein family
additional property: PropertyValue
  property ID: P527
  value: Glutathione peroxidase conserved site
additional property: PropertyValue
  property ID: P527
  value: Glutathione peroxidase active site
additional property: PropertyValue
  property ID: P637
  value: NP_110453
additional property: PropertyValue
  property ID: P680
  value: peroxidase activity
additional property: PropertyValue
  property ID: P680
  value: glutathione peroxidase activity
additional property: PropertyValue
  property ID: P680
  value: oxidoreductase activity
additional property: PropertyValue
  property ID: P681
  value: nucleus
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P682
  value: glutathione metabolic process
additional property: PropertyValue
  property ID: P682
  value: response to oxidative stress
additional property: PropertyValue
  property ID: P682
  value: ageing
additional property: PropertyValue
  property ID: P702
  value: Gpx1
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000066577
confidence:
  popularity graph score:
    score: 0.003
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 24
      unique citations norm: 0.009
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 24
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P04041
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797370
    source count: 1
    confidence: 0.2
    value label: Thioredoxin-like superfamily
  P361:
    value: Q24773045
    source count: 1
    confidence: 0.2
    value label: glutathione peroxidase
  P361:
    value: Q95353282
    source count: 1
    confidence: 0.2
    value label: Glutathione peroxidase active site, protein family
  P361:
    value: Q95353421
    source count: 1
    confidence: 0.2
    value label: Glutathione peroxidase conserved site, protein family
  P527:
    value: Q24774182
    source count: 1
    confidence: 0.2
    value label: Glutathione peroxidase conserved site
  P527:
    value: Q24724375
    source count: 1
    confidence: 0.2
    value label: Glutathione peroxidase active site
  P637:
    value: NP_110453
    source count: 1
    confidence: 0.2
  P680:
    value: Q14819650
    source count: 1
    confidence: 0.2
    value label: peroxidase activity
  P680:
    value: Q14889539
    source count: 4
    confidence: 0.8
    value label: glutathione peroxidase activity
  P680:
    value: Q14349613
    source count: 1
    confidence: 0.2
    value label: oxidoreductase activity
  P680:
    value: Q14819650
    source count: 2
    confidence: 0.4
    value label: peroxidase activity
  P680:
    value: Q14889539
    source count: 5
    confidence: 1.0
    value label: glutathione peroxidase activity
  P681:
    value: Q40260
    source count: 1
    confidence: 0.2
    value label: nucleus
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q39572
    source count: 1
    confidence: 0.2
    value label: mitochondrion
  P681:
    value: Q220599
    source count: 1
    confidence: 0.2
    value label: cytosol
  P681:
    value: Q39572
    source count: 2
    confidence: 0.4
    value label: mitochondrion
  P682:
    value: Q14877628
    source count: 1
    confidence: 0.2
    value label: glutathione metabolic process
  P682:
    value: Q14599315
    source count: 1
    confidence: 0.2
    value label: response to oxidative stress
  P682:
    value: Q332154
    source count: 1
    confidence: 0.2
    value label: ageing
  P682:
    value: Q14599419
    source count: 1
    confidence: 0.2
    value label: response to hormone

value: Q14864022
source count: 1
confidence: 0.2
value label: response to glucose

value: Q24397316
source count: 1
confidence: 0.2
value label: Gpx1

value: Q184224
source count: 1
confidence: 0.2
value label: brown rat

value: ENSRNOP00000066577
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2018-01-01

source: Dietary Selenium Stabilizes Glutathione Peroxidase mRNA in Rat Liver
stated in qid: Q28580027
retrieved: 2018-01-01

source: Dietary selenium requirements based on glutathione peroxidase-1 activity and mRNA levels and other Se-dependent parameters are not increased by pregnancy and lactation in rats
stated in qid: Q28565753
retrieved: 2018-01-01

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Dietary selenium requirements based on glutathione peroxidase-1 activity and mRNA levels and other Se-dependent parameters are not increased by pregnancy and lactation in rats
stated in qid: Q28565753
retrieved: 2019-02-14

source: Dietary Selenium Stabilizes Glutathione Peroxidase mRNA in Rat Liver
stated in qid: Q28580027
retrieved: 2019-02-14

source: Differential expression of glutathione reductase and cytosolic glutathione peroxidase, GPX1, in developing rat lungs and kidneys
stated in qid: Q28570647
retrieved: 2019-02-14

source: Expression of hepatic antioxidant genes in l-thyroxine-induced hyperthyroid rats: regulation by vitamin E and curcumin
stated in qid: Q28584021
retrieved: 2018-01-01

source: Expression of hepatic antioxidant genes in l-thyroxine-induced hyperthyroid rats: regulation by vitamin E and curcumin
stated in qid: Q28584021
retrieved: 2019-02-14

source: Spermatozoa have decreased antioxidant enzymatic capacity and increased reactive oxygen species production during aging in the Brown Norway rat
stated in qid: Q28567922
retrieved: 2019-02-14

source: Differential expression profiles of antioxidant enzymes and glutathione redox status in hyperthyroid rats: a temporal analysis
stated in qid: Q28564430
retrieved: 2019-02-14

source: Effect of high glucose on gene expression in mesangial cells: upregulation of the thiol pathway is an adaptational response
stated in qid: Q28582870
retrieved: 2019-02-14

source: Selenium requirements are higher for glutathione peroxidase-1 mRNA than gpx1 activity in rat testis
stated in qid: Q28565215
retrieved: 2018-01-01

source: DNA low-density array analysis of colchicine neurotoxicity in rat cerebellar granular neurons
stated in qid: Q28565581
retrieved: 2019-02-14

source: Effect of oestrogen on reactive oxygen species production in the aortas of ovariectomized Dahl salt-sensitive rats
stated in qid: Q28574145
retrieved: 2019-02-14

source: Maternal nicotine exposure increases oxidative stress in the offspring
stated in qid: Q28578947
retrieved: 2019-02-14

source: Proteomic analysis reveals changes in the liver protein pattern of rats exposed to dietary folate deficiency
stated in qid: Q28571237
retrieved: 2019-02-14

source: O-GlcNAcylation regulates hyperglycemia-induced GPX1 activation
stated in qid: Q28564367
retrieved: 2019-02-14

source: Selenium requirements are higher for glutathione peroxidase-1 mRNA than gpx1 activity in rat testis
stated in qid: Q28565215
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q28562393
domain: protein
level: standard
html url: https://4ort.xyz/entity/glutathione-peroxidase-1-q28562393
markdown url: https://4ort.xyz/entity/glutathione-peroxidase-1-q28562393.md
facts url summary: https://4ort.xyz/entity/glutathione-peroxidase-1-q28562393/facts.json
facts url standard: https://4ort.xyz/entity/glutathione-peroxidase-1-q28562393/facts.json
facts url full: https://4ort.xyz/entity/glutathione-peroxidase-1-q28562393/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-03T00:35:31.387363Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:58:40.809833+00:00Z