# Glutathione peroxidase 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981126](https://www.wikidata.org/wiki/Q21981126)  
**Source**: https://4ort.xyz/entity/glutathione-peroxidase-1-q21981126


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P11352)
3. Q20641742
4. [SelT, SelW, SelH, and Rdx12: genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
7. [Low glutathione peroxidase activity in Gpx1 knockout mice protects jejunum crypts from gamma-irradiation damage](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
8. [Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
9. [Cellular glutathione peroxidase deficiency and endothelial dysfunction](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
10. [Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
11. [The effect of aging on glutathione peroxidase-i knockout mice-resistance of the lens to oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
12. [Effects of dietary iron overload on glutathione peroxidase knockout mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
13. [Mice with combined disruption of Gpx1 and Gpx2 genes have colitis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
14. [Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
15. [Glutathione peroxidase knockout mice are susceptible to myocardial ischemia reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
16. [Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
17. [Targeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
18. [Microflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
19. [The nature of antioxidant defense mechanisms: a lesson from transgenic studies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
20. [Developmental changes in murine brain antioxidant enzymes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
21. [Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
23. [Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
24. [The effect of aging on glutathione peroxidase-i knockout mice-resistance of the lens to oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
25. [Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
26. [Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
27. [The nature of antioxidant defense mechanisms: a lesson from transgenic studies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
28. [Targeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
29. [Glutathione peroxidase knockout mice are susceptible to myocardial ischemia reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
30. [Effects of dietary iron overload on glutathione peroxidase knockout mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
31. [Low glutathione peroxidase activity in Gpx1 knockout mice protects jejunum crypts from gamma-irradiation damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
32. [Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
33. [Cellular glutathione peroxidase deficiency and endothelial dysfunction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
34. [Microflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
35. [Mice with combined disruption of Gpx1 and Gpx2 genes have colitis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
36. [Developmental changes in murine brain antioxidant enzymes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
37. [Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
38. [Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
39. [The Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liver](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
40. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
41. [Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352)
42. [Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
43. [The Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
44. [Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
45. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
46. [Normal remodeling of the oxygen-injured lung requires the cyclin-dependent kinase inhibitor p21(Cip1/WAF1/Sdi1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
47. [Glutathione-peroxidase-1 null muscle progenitor cells are globally defective](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
48. [Retinal light damage: structural and functional effects of the antioxidant glutathione peroxidase-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
49. [Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)
50. [Diminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352)