# Glutamate ionotropic receptor NMDA type subunit 2A

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561858](https://www.wikidata.org/wiki/Q28561858)  
**Source**: https://4ort.xyz/entity/glutamate-ionotropic-receptor-nmda-type-subunit-2a


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q00959)
3. Q20641742
4. [The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
5. [Pharmacological characterization of recombinant NR1/NR2A NMDA receptors with truncated and deleted carboxy termini expressed in Xenopus laevis oocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
7. [Prenatal development of NMDA receptor composition and function in trigeminal neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
8. [Structural Determinants of Agonist Efficacy at the Glutamate Binding Site of N-Methyl-D-Aspartate Receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
9. [Permeant ion effects on external Mg2+ block of NR1/2D NMDA receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
10. [Allosteric Interactions between NMDA Receptor Subunits Shape the Developmental Shift in Channel Properties](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
11. [Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
12. [GluN1-Specific Redox Effects on the Kinetic Mechanism of NMDA Receptor Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
14. [Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
15. [Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
16. [Interaction of the N-methyl-D-aspartate receptor complex with a novel synapse-associated protein, SAP102](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
17. [Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
18. [NMDA receptors interact with flotillin-1 and -2, lipid raft-associated proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
19. [Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
20. [Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
21. [Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
22. [Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
23. [Differential interaction of the tSXV motifs of the NR1 and NR2A NMDA receptor subunits with PSD-95 and SAP97](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
24. [NMDA receptor activation results in tyrosine phosphorylation of NMDA receptor subunit 2A(NR2A) and interaction of Pyk2 and Src with NR2A after transient cerebral ischemia and reperfusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
25. [Tyrosine kinase and tyrosine phosphatase participate in regulation of interactions of NMDA receptor subunit 2A with Src and Fyn mediated by PSD-95 after transient brain ischemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
26. [Transduced PDZ1 domain of PSD-95 decreases Src phosphorylation and increases nNOS (Ser847) phosphorylation contributing to neuroprotection after cerebral ischemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
27. [Amino Terminal Domains of the NMDA Receptor Are Organized as Local Heterodimers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
28. [An Alternating GluN1-2-1-2 Subunit Arrangement in Mature NMDA Receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
29. [A critical interaction between NR2B and MAGUK in L-DOPA induced dyskinesia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
30. [Molecular interactions of the plasma membrane calcium ATPase 2 at pre- and post-synaptic sites in rat cerebellum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
31. [ATP Induces Synaptic Gene Expressions in Cortical Neurons: Transduction and Transcription Control via P2Y1 Receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
32. [Presynaptic NR2A-containing NMDA receptors implement a high-pass filter synaptic plasticity rule](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
33. [Subunit-specific NMDA receptor trafficking to synapses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
34. [Immunoblot analyses on the differential distribution of NR2A and NR2B subunits in the adult rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
35. [Subunit- and pathway-specific localization of NMDA receptors and scaffolding proteins at ganglion cell synapses in rat retina](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
36. [Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
37. [NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
38. [The nonkinase phorbol ester receptor alpha 1-chimerin binds the NMDA receptor NR2A subunit and regulates dendritic spine density](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
39. [Tonic facilitation of glutamate release by presynaptic NR2B-containing NMDA receptors is increased in the entorhinal cortex of chronically epileptic rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
40. [Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
41. [Role of NMDA receptor subtypes in different forms of NMDA-dependent synaptic plasticity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
42. [Reaction mechanism determines NMDA receptor response to repetitive stimulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
43. [Experience-dependent regulation of NMDA receptor subunit composition and phosphorylation in the retina and visual cortex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
44. [NMDA NR2A and NR2B receptors in the rostral anterior cingulate cortex contribute to pain-related aversion in male rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
45. [Manganese exposure alters the expression of N‐methyl‐d‐aspartate receptor subunit mRNAs and proteins in rat striatum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
46. [Inhibition by 2-methoxy-4-ethylphenol of Ca2+ influx through acquired and native N-methyl-D-aspartate-receptor channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
47. [Intracerebroventricular administration of ouabain to rats changes the expression of NMDA receptor subunits in cerebral cortex and hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
48. [The effect of ketamine on N-methyl-D-aspartate receptor subunit expression in neonatal rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
49. [The potential role of phrenic nucleus glutamate receptor subunits in mediating spontaneous crossed phrenic activity in neonatal rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)
50. [Oxygen and glucose deprivation in an organotypic hippocampal slice model of the developing rat brain: the effects on N-methyl-D-aspartate subunit composition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00959)