# Glutamate ionotropic receptor NMDA type subunit 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28562649](https://www.wikidata.org/wiki/Q28562649)  
**Source**: https://4ort.xyz/entity/glutamate-ionotropic-receptor-nmda-type-subunit-1-q28562649


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P35439)
3. Q20641742
4. [Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
5. [Thyroid hormone regulation of N-methyl-D-aspartic acid receptor subunit mRNA expression in adult brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
7. [Prenatal development of NMDA receptor composition and function in trigeminal neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
8. [Permeant ion effects on external Mg2+ block of NR1/2D NMDA receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
9. [Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
10. [Apparent homomeric NR1 currents observed in Xenopus oocytes are caused by an endogenous NR2 subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
11. [Allosteric Interactions between NMDA Receptor Subunits Shape the Developmental Shift in Channel Properties](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
12. [Crystal structure of a heterotetrameric NMDA receptor ion channel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
13. [GluN1-Specific Redox Effects on the Kinetic Mechanism of NMDA Receptor Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
15. [Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
16. [The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
17. [Synaptonuclear messenger PRR7 inhibits c-Jun ubiquitination and regulates NMDA-mediated excitotoxicity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
18. [NMDA receptors interact with flotillin-1 and -2, lipid raft-associated proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
19. [Yotiao protein, a ligand for the NMDA receptor, binds and targets cAMP-dependent protein kinase II(1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
20. [TLS interaction with NMDA R1 splice variant in retinal ganglion cell line RGC-5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
21. [Activation of NMDA receptors and the mechanism of inhibition by ifenprodil](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
22. [Vangl2, the planner cell polarity protein, is complexed with postsynaptic density protein PSD‐95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
23. [Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
24. [PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
25. [Interactions between CAP70 and actinfilin are important for integrity of actin cytoskeleton structures in neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
26. [A novel family of adhesion-like molecules that interacts with the NMDA receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
27. [SAP102, a novel postsynaptic protein that interacts with NMDA receptor complexes in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
28. [Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
29. [Unique domain anchoring of Src to synaptic NMDA receptors via the mitochondrial protein NADH dehydrogenase subunit 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
30. [Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
31. [Amino Terminal Domains of the NMDA Receptor Are Organized as Local Heterodimers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
32. [An Alternating GluN1-2-1-2 Subunit Arrangement in Mature NMDA Receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
33. [Presynaptic NR2A-containing NMDA receptors implement a high-pass filter synaptic plasticity rule](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
34. [Subunit-specific NMDA receptor trafficking to synapses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
35. [Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
36. [Distribution of NMDA and AMPA receptor subunits at thalamo-amygdaloid dendritic spines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
37. [Distribution of interleukin-1 receptor complex at the synaptic membrane driven by interleukin-1β and NMDA stimulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
38. [Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
39. [Presynaptic NMDA receptors - dynamics and distribution in developing axons in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
40. [Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
41. [Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
42. [Control of excitatory and inhibitory synapse formation by neuroligins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
43. [Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
44. [Pre- and postsynaptic localization of NMDA receptor subunits at hippocampal mossy fibre synapses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
45. [Inhibition by 2-methoxy-4-ethylphenol of Ca2+ influx through acquired and native N-methyl-D-aspartate-receptor channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
46. [Intracerebroventricular administration of ouabain to rats changes the expression of NMDA receptor subunits in cerebral cortex and hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
47. [The effect of ketamine on N-methyl-D-aspartate receptor subunit expression in neonatal rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
48. [Early modifications in N-methyl-D-aspartate receptor subunit mRNA levels in an oxygen and glucose deprivation model using rat hippocampal brain slices](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
49. [Long-term exposure to endogenous levels of tributyltin decreases GluR2 expression and increases neuronal vulnerability to glutamate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)
50. [Effect of manganese exposure on intracellular Ca2+ homeostasis and expression of NMDA receptor subunits in primary cultured neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35439)