# Glucosylceramidase beta

> mammalian protein found in Homo sapiens

**Wikidata**: [Q420038](https://www.wikidata.org/wiki/Q420038)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Glucocerebrosidase)  
**Source**: https://4ort.xyz/entity/glucosylceramidase-beta


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL206468)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P04062)
4. Q20641742
5. Freebase Data Dumps. 2013
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
7. [Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
8. [Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
9. [LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
10. [Loss of β-Glucocerebrosidase Activity Does Not Affect Alpha-Synuclein Levels or Lysosomal Function in Neuronal Cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
11. [Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
12. [Involvement of acid beta-glucosidase 1 in the salvage pathway of ceramide formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
13. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
14. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
15. [Integral and associated lysosomal membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
16. [Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipid](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
17. [Mitochondrial dysfunction associated with glucocerebrosidase deficiency](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
18. [iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
19. [Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04062&geneProductId=UniProtKB:P04062)
20. Ensembl Release 99
21. Identifiers.org
22. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)