# GLI-Kruppel family member GLI2

> mammalian protein found in Mus musculus

**Wikidata**: [Q14886550](https://www.wikidata.org/wiki/Q14886550)  
**Source**: https://4ort.xyz/entity/gli-kruppel-family-member-gli2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q0VGT2)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
5. [The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
6. [The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q0VGT2&geneProductId=UniProtKB:Q0VGT2)
7. [GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
8. [Physical and functional interactions between Zic and Gli proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
9. [Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
10. [Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
11. [Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
12. [Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
13. [Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
14. [Expression of the mouse Fgf15 gene is directly initiated by Sonic hedgehog signaling in the diencephalon and midbrain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
15. [The transcription factor Foxc1 is necessary for Ihh–Gli2-regulated endochondral ossification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
16. [Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
17. [Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
18. [A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
19. [Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
20. [FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
21. [Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
22. [The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
23. [The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
24. [A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
25. [Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
26. [Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
27. [Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
28. [Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
29. [Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
30. [Anorectal malformations caused by defects in sonic hedgehog signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
31. [Mouse Rab23 regulates hedgehog signaling from smoothened to Gli proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
32. [Gli1can rescue the in vivo function ofGli2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
33. [The Gli2 Transcription Factor Is Required for Normal Mouse Mammary Gland Development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
34. [The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
35. [Functional compensation in Hedgehog signaling during mouse prostate development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
36. [PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
37. [The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
38. [Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
39. [Ventral midline cells are required for the local control of commissural axon guidance in the mouse spinal cord](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
40. [Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
41. [Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
42. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q0VGT2&geneProductId=UniProtKB:Q0VGT2)
43. [Murine models of VACTERL syndrome: Role of sonic hedgehog signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
44. [Molecular control of spinal accessory motor neuron/axon development in the mouse spinal cord](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
45. [Suppressing Wnt signaling by the hedgehog pathway through sFRP-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
46. [Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
47. [Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
48. [Complex interactions between genes controlling trafficking in primary cilia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
49. [Complementary Gli activity mediates early patterning of the mouse visual system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)
50. [IFT80 is essential for chondrocyte differentiation by regulating Hedgehog and Wnt signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q0VGT2)