# Ghrelin and obestatin prepropeptide

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28560450](https://www.wikidata.org/wiki/Q28560450)  
**Source**: https://4ort.xyz/entity/ghrelin-and-obestatin-prepropeptide


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9QYH7)
3. Q20641742
4. [Ghrelin is a growth-hormone-releasing acylated peptide from stomach](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
6. [Ghrelin augments afferent response to distension in rat isolated jejunum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
7. [Central effects of ghrelin on serum growth hormone and morphology of pituitary somatotropes in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
9. [Upregulation of cardiovascular ghrelin receptor occurs in the hyperdynamic phase of sepsis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
10. [Involvement of PKA and ERK pathways in ghrelin-induced long-lasting potentiation of excitatory synaptic transmission in the CA1 area of rat hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
11. [Ghrelin promotes reorganization of dendritic spines in cultured rat hippocampal slices](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
12. [Role of ghrelin in the regulation of gastric acid secretion involving nitrergic mechanisms in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
13. [Ghrelin Is Present in Pancreatic α-Cells of Humans and Rats and Stimulates Insulin Secretion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
14. [Obesity in MENX Rats Is Accompanied by High Circulating Levels of Ghrelin and Improved Insulin Sensitivity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
15. [Ghrelin attenuates the inhibitory effects of glucagon-like peptide-1 and peptide YY(3-36) on food intake and gastric emptying in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
16. [Anti-ghrelin Spiegelmer NOX-B11 inhibits neurostimulatory and orexigenic effects of peripheral ghrelin in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
17. [Suppression of experimental autoimmune encephalomyelitis by ghrelin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
18. [Comparison of the gastroprokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
19. [Unacylated ghrelin is active on the INS-1E rat insulinoma cell line independently of the growth hormone secretagogue receptor type 1a and the corticotropin releasing factor 2 receptor.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
20. [Influence of ghrelin on gastric and duodenal growth and expression of digestive enzymes in young mature rats.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
21. [Ghrelin inhibits apoptosis signal-regulating kinase 1 activity via upregulating heat-shock protein 70](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
22. [Pattern-dependent suppression of growth hormone (GH) pulsatility by ghrelin and GH-releasing peptide-6 in moderately GH-deficient rats.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
23. [Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
24. [Effects of ghrelin on gastric distension sensitive neurons and gastric motility in the lateral septum and arcuate nucleus regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
25. [Down-regulation of ghrelin receptors in the small intestine delays small intestinal transit in vagotomized rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
26. [The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
27. [Ghrelin Modulates Physiologic and Pathologic Retinal Angiogenesis through GHSR-1a](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
28. [Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYH7)
29. ensembl Release 106