# Geminin DNA replication inhibitor

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5530676](https://www.wikidata.org/wiki/Q5530676)  
**Source**: https://4ort.xyz/entity/geminin-dna-replication-inhibitor-q5530676


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O75496)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
6. [Emi1 preferentially inhibits ubiquitin chain elongation by the anaphase-promoting complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
7. [A WD-Repeat Protein Stabilizes ORC Binding to Chromatin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
8. [Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
9. [Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
10. [Two E3 ubiquitin ligases, SCF‐Skp2 and DDB1‐Cul4, target human Cdt1 for proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
11. [A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
12. [Idas, a Novel Phylogenetically Conserved Geminin-related Protein, Binds to Geminin and Is Required for Cell Cycle Progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
13. [Cdt1 Phosphorylation by Cyclin A-dependent Kinases Negatively Regulates Its Function without Affecting Geminin Binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
14. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
15. [Inhibition of Eukaryotic DNA Replication by Geminin Binding to Cdt1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
16. [Self-Assembling Protein Microarrays](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
17. [Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore–microtubule attachment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
18. [Pooled‐matrix protein interaction screens using Barcode Fusion Genetics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
19. [JNK1 Phosphorylation of Cdt1 Inhibits Recruitment of HBO1 Histone Acetylase and Blocks Replication Licensing in Response to Stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
21. [The histone demethylase LSD1/KDM1A promotes the DNA damage response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
22. [Geminin, an Inhibitor of DNA Replication, Is Degraded during Mitosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
23. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75496&geneProductId=UniProtKB:O75496)
24. [The APC/C inhibitor, Emi1, is essential for prevention of rereplication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75496)
25. Ensembl Release 99
26. Identifiers.org