# Gelsolin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q3098700](https://www.wikidata.org/wiki/Q3098700)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Gelsolin)  
**Source**: https://4ort.xyz/entity/gelsolin


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P06396)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
6. [Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
7. [Collagen remodeling by phagocytosis is determined by collagen substrate topology and calcium-dependent interactions of gelsolin with nonmuscle myosin IIA in cell adhesions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
8. [Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
9. [Three-dimensional structure of cofilin bound to monomeric actin derived by structural mass spectrometry data](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
10. [The structural basis of actin interaction with multiple WH2/beta-thymosin motif-containing proteins.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
11. [Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
12. [Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
13. [Functional specialization of beta-arrestin interactions revealed by proteomic analysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
14. [Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
15. [A new role for nuclear transport factor 2 and Ran: nuclear import of CapG](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
16. [L-Plastin Nanobodies Perturb Matrix Degradation, Podosome Formation, Stability and Lifetime in THP-1 Macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
17. [Identification of a polyphosphoinositide-binding sequence in an actin monomer-binding domain of gelsolin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
18. [Gelsolin domain 2 Ca2+ affinity determines susceptibility to furin proteolysis and familial amyloidosis of finnish type](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
19. [Gelsolin activity controls efficient early HIV-1 infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
21. [Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
22. [Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
23. [The human plasma proteome: a nonredundant list developed by combination of four separate sources](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
24. [Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
25. [Secretion of amyloidogenic gelsolin progressively compromises protein homeostasis leading to the intracellular aggregation of proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
26. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
27. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
28. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
29. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
30. [Protein profile of exosomes from trabecular meshwork cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
31. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
32. [The human papillomavirus-16 E7 oncoprotein exerts antiapoptotic effects via its physical interaction with the actin-binding protein gelsolin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
33. [N-Terminal Region of Gelsolin Induces Apoptosis of Activated Hepatic Stellate Cells by a Caspase-Dependent Mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
34. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
35. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
36. [Protein profile of exosomes from trabecular meshwork cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
37. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
38. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
39. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
40. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
41. [Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
42. [The human plasma proteome: a nonredundant list developed by combination of four separate sources](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
43. [Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
44. [Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
45. [Functional genomic screen for modulators of ciliogenesis and cilium length](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
46. [The crystal structure of the C-terminus of adseverin reveals the actin-binding interface.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
47. [Novel gelsolin variant as the cause of nephrotic syndrome and renal amyloidosis in a large kindred](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
48. [The 8 and 5 kDa fragments of plasma gelsolin form amyloid fibrils by a nucleated polymerization mechanism, while the 68 kDa fragment is not amyloidogenic](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396)
49. [Gelsolin activity controls efficient early HIV-1 infection](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)
50. [The human papillomavirus-16 E7 oncoprotein exerts antiapoptotic effects via its physical interaction with the actin-binding protein gelsolin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396)