# Gcn1p YGL195W

> fungal protein found in Saccharomyces cerevisiae S288c

**Wikidata**: [Q27548667](https://www.wikidata.org/wiki/Q27548667)  
**Source**: https://4ort.xyz/entity/gcn1p-ygl195w


## References

1. UniProt
2. Q20641742
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P33892)
4. [Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
6. [Gcn1 and actin binding to Yih1: implications for activation of the eIF2 kinase GCN2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
7. [GCN20, a novel ATP binding cassette protein, and GCN1 reside in a complex that mediates activation of the eIF-2 alpha kinase GCN2 in amino acid-starved cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
8. [Gcn1 contacts the small ribosomal protein Rps10, which is required for full activation of the protein kinase Gcn2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
9. [YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
10. [Evidence that Yih1 resides in a complex with ribosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
11. [Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
12. [Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
13. [Proteome survey reveals modularity of the yeast cell machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
14. [Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
15. [Evidence that GCN1 and GCN20, Translational Regulators of GCN4, Function on Elongating Ribosomes in Activation of eIF2α Kinase GCN2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
16. [Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
17. [Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
18. [The proteome of Saccharomyces cerevisiae mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
19. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P33892&geneProductId=UniProtKB:P33892)
20. [GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
21. [Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
22. [General Control Nonderepressible 2 (GCN2) Kinase Inhibits Target of Rapamycin Complex 1 in Response to Amino Acid Starvation in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33892)
23. ensembl Release 106