# Gawky Dmel_CG31992

> protein found in Drosophila melanogaster

**Wikidata**: [Q29809721](https://www.wikidata.org/wiki/Q29809721)  
**Source**: https://4ort.xyz/entity/gawky-dmel-cg31992


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8SY33)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
5. [A C-terminal silencing domain in GW182 is essential for miRNA function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
6. [GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
7. [The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
8. [GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
9. [The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
10. [Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
11. [mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
12. [PABP is not essential for microRNA-mediated translational repression and deadenylation in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
13. [Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8SY33&geneProductId=UniProtKB:Q8SY33)
15. [P-body formation is a consequence, not the cause, of RNA-mediated gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8SY33&geneProductId=UniProtKB:Q8SY33)
16. [Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8SY33&geneProductId=UniProtKB:Q8SY33)
17. [Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
18. [P-body formation is a consequence, not the cause, of RNA-mediated gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
20. [Silencio/CG9754 connects the Piwi-piRNA complex to the cellular heterochromatin machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
21. [A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
22. [The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8SY33&geneProductId=UniProtKB:Q8SY33)
23. [GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8SY33&geneProductId=UniProtKB:Q8SY33)
24. [The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8SY33&geneProductId=UniProtKB:Q8SY33)
25. [Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8SY33&geneProductId=UniProtKB:Q8SY33)
26. [The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8SY33&geneProductId=UniProtKB:Q8SY33)
27. [A C-terminal silencing domain in GW182 is essential for miRNA function](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8SY33&geneProductId=UniProtKB:Q8SY33)
28. [mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8SY33&geneProductId=UniProtKB:Q8SY33)
29. [A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8SY33&geneProductId=UniProtKB:Q8SY33)
30. [GW182 Controls Drosophila Circadian Behavior and PDF-Receptor Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
31. [Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
32. [The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
33. [LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8SY33)
34. ensembl Release 106