# GATA binding protein 6

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21101548](https://www.wikidata.org/wiki/Q21101548)  
**Source**: https://4ort.xyz/entity/gata-binding-protein-6


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q92908)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
7. [GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
8. [GATA-4 and GATA-6 modulate tissue-specific transcription of the human gene for P450c17 by direct interaction with Sp1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
9. [Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
10. [Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
11. [Calcineurin-GATA-6 pathway is involved in smooth muscle-specific transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
12. [PTEN differentially regulates expressions of ICAM-1 and VCAM-1 through PI3K/Akt/GSK-3β/GATA-6 signaling pathways in TNF-α-activated human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
13. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
14. [GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor beta/activin receptor-like kinase 5 signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
16. [GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
17. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
18. [GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor beta/activin receptor-like kinase 5 signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
19. [Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
20. [Calcineurin-GATA-6 pathway is involved in smooth muscle-specific transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
21. [GATA-4 and GATA-6 modulate tissue-specific transcription of the human gene for P450c17 by direct interaction with Sp1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
22. [Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
23. [GATA-6 Induces p21Cip1 Expression and G1Cell Cycle Arrest](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
24. [Transcription factor GATA-6 in the human adrenocortex: association with adrenal development and aging](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
25. [Gain-of-function mutations in GATA6 lead to atrial fibrillation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
26. [The transcription factor GATA-4 regulates cytochrome P4502C19 gene expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
27. [Distinct Functions Are Implicated for the GATA-4, -5, and -6 Transcription Factors in the Regulation of Intestine Epithelial Cell Differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
28. [HEB and E2A function as SMAD/FOXH1 cofactors](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
29. [The transcription factor GATA-4 regulates cytochrome P4502C19 gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
30. [Gain-of-function mutations in GATA6 lead to atrial fibrillation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
31. [Transcription factor GATA-6 in the human adrenocortex: association with adrenal development and aging](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
32. [GATA-6 Induces p21Cip1 Expression and G1Cell Cycle Arrest](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
33. [Distinct Functions Are Implicated for the GATA-4, -5, and -6 Transcription Factors in the Regulation of Intestine Epithelial Cell Differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
34. [HEB and E2A function as SMAD/FOXH1 cofactors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
35. [Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
36. [GATA-6 is involved in PPARgamma-mediated activation of differentiated phenotype in human vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
37. [GATA-6 is a novel transcriptional repressor of the human Tenascin-C gene expression in fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
38. [GATA-6 mediates human bladder smooth muscle differentiation: involvement of a novel enhancer element in regulating alpha-smooth muscle actin gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
39. [The mediator complex subunit 1 enhances transcription of genes needed for adrenal androgen production](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92908&geneProductId=UniProtKB:Q92908)
40. [GATA6 loss-of-function mutation in atrial fibrillation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
41. [Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
42. [miR-10a Regulates Proliferation of Human Cardiomyocyte Progenitor Cells by Targeting GATA6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92908)
43. Ensembl Release 99
44. UMLS 2023