# GATA binding protein 4

> mammalian protein found in Mus musculus

**Wikidata**: [Q21497814](https://www.wikidata.org/wiki/Q21497814)  
**Source**: https://4ort.xyz/entity/gata-binding-protein-4-q21497814


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q08369)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
5. [SOX7 and GATA-4 are competitive activators of Fgf-3 transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
6. [Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
7. [Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
8. [Gata4 and Sp1 regulate expression of the erythropoietin receptor in cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
9. [The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
10. [GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
11. [The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
12. [UTX, a Histone H3-Lysine 27 Demethylase, Acts as a Critical Switch to Activate the Cardiac Developmental Program](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
13. [Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
14. [Hopx and Hdac2 Interact to Modulate Gata4 Acetylation and Embryonic Cardiac Myocyte Proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
15. [Analysis of the signals and mechanisms mediating nuclear trafficking of GATA-4. Loss of DNA binding is associated with localization in intranuclear speckles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
16. [Baf60c is essential for function of BAF chromatin remodelling complexes in heart development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
17. [The Cardiac Tissue-Restricted Homeobox Protein Csx/Nkx2.5 Physically Associates with the Zinc Finger Protein GATA4 and Cooperatively Activates Atrial Natriuretic Factor Gene Expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
18. [Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
19. [Defects of the Heart, Eye, and Megakaryocytes in Peroxisome Proliferator Activator Receptor-binding Protein (PBP) Null Embryos Implicate GATA Family of Transcription Factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
20. [Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
21. [Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
22. [Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
23. [The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
24. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
25. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
26. [The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
27. [Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
28. [GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
29. [Analysis of the signals and mechanisms mediating nuclear trafficking of GATA-4. Loss of DNA binding is associated with localization in intranuclear speckles](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
30. [Distinct gene expression patterns in skeletal and cardiac muscle are dependent on common regulatory sequences in the MLC1/3 locus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
31. [Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
32. [Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
33. [SOX7 and GATA-4 are competitive activators of Fgf-3 transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
34. [Gata4 and Sp1 regulate expression of the erythropoietin receptor in cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
35. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
36. [Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
37. [Distinct Functions Are Implicated for the GATA-4, -5, and -6 Transcription Factors in the Regulation of Intestine Epithelial Cell Differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
38. [Dynamics of ovarian development in the FORKO immature mouse: structural and functional implications for ovarian reserve](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
39. [The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
40. [Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
41. [Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
42. [Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
43. [Loss-of-function mutation in GATA4 causes anomalies of human testicular development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08369&geneProductId=UniProtKB:Q08369)
44. [Distinct Functions Are Implicated for the GATA-4, -5, and -6 Transcription Factors in the Regulation of Intestine Epithelial Cell Differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
45. [Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
46. [The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
47. [Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
48. [Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
49. [Dynamics of ovarian development in the FORKO immature mouse: structural and functional implications for ovarian reserve](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)
50. [Loss-of-function mutation in GATA4 causes anomalies of human testicular development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08369)