# GATA binding protein 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21101536](https://www.wikidata.org/wiki/Q21101536)  
**Source**: https://4ort.xyz/entity/gata-binding-protein-3-q21101536


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P23771)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
5. [Lymphoid enhancer factor interacts with GATA-3 and controls its function in T helper type 2 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
7. [The human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
8. [Abundant expression of Kallikrein 1 gene in human keratinocytes was mediated by GATA3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
9. [Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
10. [Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
11. [A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
12. [NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
13. [T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
14. [c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
15. [Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2-Nucleated Repression Programs Contributes to Breast Cancer Metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
16. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
17. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
18. [Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
19. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
20. [Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
21. [Structure and expression of the human GATA3 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
22. [A T-cell specific TCR delta DNA binding protein is a member of the human GATA family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
23. [GATA3 siRNA inhibits the binding of NFAT1 to interleukin-13 promoter in human T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
24. [The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
25. [GATA3 Inhibits Breast Cancer Metastasis through the Reversal of Epithelial-Mesenchymal Transition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
26. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
27. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
28. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
29. [Structure and expression of the human GATA3 gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
30. [A T-cell specific TCR delta DNA binding protein is a member of the human GATA family](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
31. [GATA3 siRNA inhibits the binding of NFAT1 to interleukin-13 promoter in human T cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
32. [The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
33. [GATA3 Inhibits Breast Cancer Metastasis through the Reversal of Epithelial-Mesenchymal Transition](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
34. [Abundant expression of Kallikrein 1 gene in human keratinocytes was mediated by GATA3](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
35. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
36. [c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
37. [A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
38. [Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
39. [Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
40. [HDR syndrome: a novel "de novo" mutation in GATA3 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
41. [GATA3 is a master regulator of the transcriptional response to low-dose ionizing radiation in human keratinocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
42. [Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
43. [GATA3 inhibits breast cancer growth and pulmonary breast cancer metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
44. [GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
45. [GATA3 haplo-insufficiency causes human HDR syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
46. [T-bet, GATA-3, and Foxp3 expression and Th1/Th2 cytokine production in the clinical outcome of human infection with Leishmania (Viannia) species](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
47. [Combining SSH and cDNA microarrays for rapid identification of differentially expressed genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
48. [Activation of the Interleukin-5 Promoter by cAMP in Murine EL-4 Cells Requires the GATA-3 and CLE0 Elements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771)
49. [Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771)
50. Ensembl Release 99