# GATA binding protein 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5512896](https://www.wikidata.org/wiki/Q5512896)  
**Source**: https://4ort.xyz/entity/gata-binding-protein-1-q5512896


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P15976)
3. Q20641742
4. [Swiss-Prot](http://www.uniprot.org/uniprot/P17679.txt?version=155)
5. [Molecular cloning and characterization of the GATA1 cofactor human FOG1 and assessment of its binding to GATA1 proteins carrying D218 substitutions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
6. [Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
7. [X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
9. [Developmental silencing of human zeta-globin gene expression is mediated by the transcriptional repressor RREB1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
10. [Knockdown of ZNF268, which Is Transcriptionally Downregulated by GATA-1, Promotes Proliferation of K562 Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
11. [A novel erythroid differentiation related gene EDRF1 upregulating globin gene expression in HEL cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
12. [A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
13. [Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
15. [Increased gamma-globin expression in a nondeletion HPFH mediated by an erythroid-specific DNA-binding factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
16. [Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
17. [A Novel In-Frame Deletion in the Leucine Zipper Domain of C/EBPε Leads to Neutrophil-Specific Granule Deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
18. [CCAR1/CoCoA pair‐mediated recruitment of the Mediator defines a novel pathway for GATA1 function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
19. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
20. [The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
21. [Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
22. [GATA-1 forms distinct activating and repressive complexes in erythroid cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
23. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
24. [Developmental silencing of human zeta-globin gene expression is mediated by the transcriptional repressor RREB1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
25. [GATA-1 forms distinct activating and repressive complexes in erythroid cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
26. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
27. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
28. [Increased gamma-globin expression in a nondeletion HPFH mediated by an erythroid-specific DNA-binding factor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
29. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
30. [Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
31. [Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
32. [Essential and instructive roles of GATA factors in eosinophil development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
33. [Selective impairment of platelet activation to collagen in the absence of GATA1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
34. [GAR22: a novel target gene of thyroid hormone receptor causes growth inhibition in human erythroid cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
35. [Expression of tal-1 and GATA-binding proteins during human hematopoiesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
36. [X-linked thrombocytopenia caused by a novel mutation of GATA-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
37. [X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
38. [Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976)
39. [Knockdown of ZNF268, which Is Transcriptionally Downregulated by GATA-1, Promotes Proliferation of K562 Cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
40. [Selective impairment of platelet activation to collagen in the absence of GATA1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
41. [Expression of tal-1 and GATA-binding proteins during human hematopoiesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
42. [Molecular cloning and characterization of the GATA1 cofactor human FOG1 and assessment of its binding to GATA1 proteins carrying D218 substitutions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
43. [X-linked thrombocytopenia caused by a novel mutation of GATA-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976)
44. Ensembl Release 99
45. UMLS 2023