# Gap junction protein alpha 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q2356259](https://www.wikidata.org/wiki/Q2356259)  
**Source**: https://4ort.xyz/entity/gap-junction-protein-alpha-1


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P17302)
4. Q20641742
5. Freebase Data Dumps. 2013
6. [Molecular characterization and functional expression of the human cardiac gap junction channel](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
8. [Novel rab GAP-like protein, CIP85, interacts with connexin43 and induces its degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
9. [The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
10. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
11. [Interaction of zonula occludens-1 (ZO-1) with alpha-actinin-4: application of functional proteomics for identification of PDZ domain-associated proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
12. [A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
13. [Novel GermlineGJA5/Connexin40 Mutations Associated with Lone Atrial Fibrillation Impair Gap Junctional Intercellular Communication](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
14. [Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
15. [Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
16. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
17. [Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
18. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
19. [Functional analysis of human cardiac gap junction channel mutants](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
20. [Basic Mechanisms of Cardiac Impulse Propagation and Associated Arrhythmias](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
21. [Detection of genomic deletions of PKP2 in arrhythmogenic right ventricular cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
22. [Mutated desmoglein-2 proteins are incorporated into desmosomes and exhibit dominant-negative effects in arrhythmogenic right ventricular cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
23. [Mutations of the Connexin43 gap-junction gene in patients with heart malformations and defects of laterality](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17302&geneProductId=UniProtKB:P17302)
24. ensembl Release 93