Gamma-aminobutyric acid type A receptor subunit alpha5
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
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  value: protein
additional property: PropertyValue
  property ID: P129
  value: gaboxadol
additional property: PropertyValue
  property ID: P129
  value: isonipecotic acid
additional property: PropertyValue
  property ID: P129
  value: isoguvacine
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  property ID: P352
  value: P31644
additional property: PropertyValue
  property ID: P361
  value: Neurotransmitter-gated ion-channel ligand-binding domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Neurotransmitter-gated ion-channel transmembrane domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Gamma-aminobutyric-acid A receptor, alpha 5 subunit
additional property: PropertyValue
  property ID: P527
  value: Neurotransmitter-gated ion-channel transmembrane domain
additional property: PropertyValue
  property ID: P527
  value: Neurotransmitter-gated ion-channel ligand-binding domain
additional property: PropertyValue
  property ID: P527
  value: Neurotransmitter-gated ion-channel, conserved site
additional property: PropertyValue
  property ID: P637
  value: NP_000801
additional property: PropertyValue
  property ID: P637
  value: NP_001158509
additional property: PropertyValue
  property ID: P637
  value: XP_005268315
additional property: PropertyValue
  property ID: P680
  value: GABA-A receptor activity
additional property: PropertyValue
  property ID: P680
  value: transporter activity
additional property: PropertyValue
  property ID: P680
  value: ion channel activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: cell body
additional property: PropertyValue
  property ID: P681
  value: GABA-A receptor complex
additional property: PropertyValue
  property ID: P682
  value: gamma-aminobutyric acid signaling pathway
additional property: PropertyValue
  property ID: P682
  value: negative regulation of neuron apoptotic process
additional property: PropertyValue
  property ID: P682
  value: cochlea development
additional property: PropertyValue
  property ID: P702
  value: GABRA5
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000335592
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  property ID: P705
  value: ENSP00000347557
additional property: PropertyValue
  property ID: P705
  value: ENSP00000382953
additional property: PropertyValue
  property ID: P7260
  value: 1.A.9.5.2
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 10
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 10
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P129:
    value: Q4130924
    source count: 1
    confidence: 0.2
    value label: gaboxadol
  P129:
    value: Q15239768
    source count: 1
    confidence: 0.2
    value label: isonipecotic acid
  P129:
    value: Q6085784
    source count: 1
    confidence: 0.2
    value label: isoguvacine
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    value: Q412504
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    value label: muscimol
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    source count: 1
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    value label: ZK93423
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    value: P31644
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797834
    source count: 1
    confidence: 0.2
    value label: Neurotransmitter-gated ion-channel ligand-binding domain superfamily
  P361:
    value: Q41797819
    source count: 1
    confidence: 0.2
    value label: Neurotransmitter-gated ion-channel transmembrane domain superfamily
  P361:
    value: Q24782783
    source count: 1
    confidence: 0.2
    value label: Gamma-aminobutyric-acid A receptor, alpha 5 subunit
  P361:
    value: Q83138959
    source count: 1
    confidence: 0.2
    value label: Neurotransmitter-gated ion-channel transmembrane domain, protein family
  P361:
    value: Q83136602
    source count: 1
    confidence: 0.2
    value label: Neurotransmitter-gated ion-channel ligand-binding domain, protein family
  P527:
    value: Q24767169
    source count: 1
    confidence: 0.2
    value label: Neurotransmitter-gated ion-channel transmembrane domain
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    value: Q24739230
    source count: 1
    confidence: 0.2
    value label: Neurotransmitter-gated ion-channel ligand-binding domain
  P527:
    value: Q24725894
    source count: 1
    confidence: 0.2
    value label: Neurotransmitter-gated ion-channel, conserved site
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  P637:
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  P637:
    value: XP_006720522
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  P637:
    value: XP_016877544
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value: Q21113291
source count: 3
confidence: 0.6
value label: GABA-A receptor activity

value: Q14864384
source count: 1
confidence: 0.2
value label: transporter activity

value: Q14864714
source count: 1
confidence: 0.2
value label: ion channel activity

value: Q14864705
source count: 1
confidence: 0.2
value label: chloride channel activity

value: Q21103163
source count: 1
confidence: 0.2
value label: extracellular ligand-gated ion channel activity

value: Q14327652
source count: 2
confidence: 0.4
value label: integral component of membrane

value: Q14864866
source count: 1
confidence: 0.2
value label: cell body

value: Q21113294
source count: 1
confidence: 0.2
value label: GABA-A receptor complex

value: Q14864257
source count: 1
confidence: 0.2
value label: postsynaptic membrane

value: Q14349455
source count: 3
confidence: 0.6
value label: membrane

value: Q21102115
source count: 1
confidence: 0.2
value label: gamma-aminobutyric acid signaling pathway

value: Q14820618
source count: 1
confidence: 0.2
value label: negative regulation of neuron apoptotic process

value: Q14897879
source count: 1
confidence: 0.2
value label: cochlea development

value: Q14330970
source count: 1
confidence: 0.2
value label: associative learning

value: Q14818122
source count: 1
confidence: 0.2
value label: regulation of neuron apoptotic process

value: Q18025082
source count: 1
confidence: 0.2
value label: GABRA5

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000335592
source count: 1
confidence: 0.2

value: ENSP00000347557
source count: 1
confidence: 0.2

value: ENSP00000382953
source count: 1
confidence: 0.2

value: ENSP00000450529
source count: 1
confidence: 0.2

value: ENSP00000450653
source count: 1
confidence: 0.2

value: 1.A.9.5.2
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Cloning and expression of a cDNA encoding the human GABA-A receptor alpha 5 subunit
stated in qid: Q24336885
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-07-16

source: Cloning and expression of a cDNA encoding the human GABA-A receptor alpha 5 subunit
stated in qid: Q24336885
retrieved: 2018-07-16

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: IUPHAR/BPS Guide to PHARMACOLOGY
stated in qid: Q17091219
retrieved: 2016-08-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21114576
domain: protein
level: standard
html url: https://4ort.xyz/entity/gamma-aminobutyric-acid-type-a-receptor-subunit-alpha5-q21114576
markdown url: https://4ort.xyz/entity/gamma-aminobutyric-acid-type-a-receptor-subunit-alpha5-q21114576.md
facts url summary: https://4ort.xyz/entity/gamma-aminobutyric-acid-type-a-receptor-subunit-alpha5-q21114576/facts.json
facts url standard: https://4ort.xyz/entity/gamma-aminobutyric-acid-type-a-receptor-subunit-alpha5-q21114576/facts.json
facts url full: https://4ort.xyz/entity/gamma-aminobutyric-acid-type-a-receptor-subunit-alpha5-q21114576/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-05T17:57:33.207078Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:25:56.647217+00:00Z